Dement Neurocogn Disord.  2023 Jan;22(1):16-27. 10.12779/dnd.2023.22.1.16.

Diagnostic Tools for Alzheimer’s Disease: A Narrative Review Based on Our Own Research Experience

Affiliations
  • 1Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea
  • 2Center for Geriatric Neuroscience Research, Institute of Biomedical Science and Technology, Konkuk University School of Medicine, Seoul, Korea
  • 3Department of Neurology, Konkuk University School of Medicine, Seoul, Korea
  • 4Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 5Department of Radiology, Konkuk University School of Medicine, Seoul, Korea
  • 6Department of Neurology, Kangwon National University Hospital, Kangwon National University, Chuncheon, Korea

Abstract

Alzheimer’s disease (AD), one of the most representative neurodegenerative diseases, has diverse neurobiological and pathophysiological mechanisms. Treatment strategies targeting a single mechanism have repeated faced failures because the mechanism of neuronal cell death is very complex that is not fully understood yet. Since complex mechanisms exist to explain AD, a variety of diagnostic biomarkers for diagnosing AD are required. Moreover, standardized evaluations for comprehensive diagnosis using neuropsychological, imaging, and laboratory tools are needed. In this review, we summarize the latest clinical, neuropsychological, imaging, and laboratory evaluations to diagnose patients with AD based on our own experience in conducting a prospective study.

Keyword

Dementia; Biomarkers; Diagnosis
Full Text Links
  • DND
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr