J Korean Neurol Assoc.  2023 Aug;41(3):210-215. 10.17340/jkna.2023.3.6.

Lexical-semantic Deficit without Semantic Impairment in a Patient with Left Anterior Choroidal Artery Infarction: Neural Correlates Based on Diffusion-tensor Tractography

Affiliations
  • 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
  • 2Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 3Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, Korea
  • 4Department of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 5Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea

Abstract

A 35-year-old male presented with atypical aphasia following left anterior choroidal artery infarction associated with distal internal carotid artery dissection. He presented with 1) lexical-semantic deficit without semantic impairment, 2) frequent surface errors (both surface dyslexia and dysgraphia), and 3) intact non-word reading/repetition (preserved sub-lexical route), suggesting deficit in the phonological output lexicon. Diffusion-tensor tractography analysis revealed disruption in the inferior fronto-occipital fasciculus and inferior longitudinal fasciculus, which might serve as potential subcortical neural correlates for phonological output lexicon.

Keyword

Anomia; Cerebral infarction; Diffusion tensor imaging
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