J Vet Sci.
2023 May;24(3):e39. 10.4142/jvs.22328.
Ectopic insulinoma in a dog with insulin-induced hypoglycemia: a case report
- Affiliations
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- 1Department of Veterinary Medical Imaging, College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea
- 2Bundang Leaders Animal Medical Center, Seongnam 13636, Korea
- 3Institute of Animal Transplantation, Jeonbuk National University, Iksan 54596, Korea
- KMID: 2542997
- DOI: http://doi.org/10.4142/jvs.22328
Abstract
- A 7-year-old spayed female Shih Tzu dog was presented for evaluation of recurrent hypoglycemia. Serum insulin levels during hypoglycemia were 35.3 μIU/mL. Ultrasonography and computed tomography showed a mesenteric nodule between the kidney and the portal vein, but no pancreatic mass was observed. During surgery, the nodule had neither anatomical adhesions nor vascular connections to the pancreas. Pancreatic inspection and palpation revealed no abnormalities. Hypoglycemia improved after resection of the nodule. Histopathological examination confirmed the nodule to be an islet cell carcinoma. Although extremely rare, ectopic insulinoma should be considered as a possible cause of insulininduced hypoglycemia in dogs.
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