J Korean Soc Radiol.  2023 May;84(3):686-691. 10.3348/jksr.2022.0058.

Immunoglobulin G4-Related Myocarditis with Eosinophilic Infiltration: A Case Report

Affiliations
  • 1Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea
  • 2Department of Cardiology in Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea

Abstract

Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a fibroinflammatory disorder that can involve any organ system; however, myocarditis is extremely rare. A 52-year-old male with dyspnea and chest discomfort underwent cardiac MRI that revealed edema and nodular, patchy, mesocardial and subendoardial delayed enhancement of left ventricle, suggesting myocarditis. Laboratory findings revealed elevated serum IgG4 and eosinophilia. Cardiac biopsy confirmed eosinophilic myocarditis with IgG4-positive cells. Here, we present an unusual case of IgG4-RD manifesting as eosinophilic myocarditis.

Keyword

Immunoglobulin G4-Related Disease; Inifltration, Eosinophil; Myocarditis; Computed Tomography; Magnetic Resonance
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