Clin Endosc.  2022 Nov;55(6):810-814. 10.5946/ce.2021.003.

Extracutaneous mastocytoma of colon: a case report and literature review

• Chu MS
• Kim EJ

• KMID: 2536082
• DOI: http://doi.org/10.5946/ce.2021.003

Abstract

Extracutaneous mastocytoma is a rare benign tumor composed of mature mast cells and is located in tissues other than the skin. We report the case of a 61-year-old male who was diagnosed with extracutaneous mastocytoma via colonoscopic polypectomy and biopsy. To our knowledge, this was the first case of a solitary extracutaneous mastocytoma of the colon. We reported this case and reviewed the literature.

Keyword

Colon; Extracutaneous mastocytoma; Mast cell; Polypectomy

Figure

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  Fig. 1. Serial images of colonoscopic polypectomy. (A) Colonoscopic image showing slightly elevated whitish gyral pattern mass. (B, C) Endoscopic resection was attempted and en bloc resection was performed. (D) Complete resection was achieved without any residual tissue.

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  Fig. 2. Histologic features of the endoscopically resected specimen. (A) Diffuse infiltration of monotonous small round cells (hematoxylin and eosin, ×100). (B) Positive staining for c-kit (immunohistochemistry, ×100). (C) Positive staining for leukocyte common antigen (immunohistochemistry, ×100). (D) Positive staining for CD68 (immunohistochemistry, ×100).

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  Fig. 3. Histologic images taken at high-power field. (A) Diffuse infiltration of monotonous small round cells (hematoxylin and eosin, ×400). (B) Cytoplasmic staining with membrane accentuation for c-kit (immunohistochemistry, ×400).

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