Korean J Intern Med.
2022 Nov;37(6):1099-1110. 10.3904/kjim.2022.168.
Musculoskeletal complications in patients with diabetes mellitus
- Affiliations
-
- 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
- 2Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
- KMID: 2535976
- DOI: http://doi.org/10.3904/kjim.2022.168
Abstract
- Musculoskeletal conditions are common in patients with diabetes. Several musculoskeletal disorders are viewed as chronic complications of diabetes because epidemiological studies have revealed high correlations between such complications and diabetes, but the pathophysiological links with diabetes remains unclear. Genetic predispositions, shared risk factors, microvascular impairments, progressive accumulation of advanced glycation end-products, and diabetic neuropathy may underlie the development of musculoskeletal disorders. Musculoskeletal complications of diabetics have received less attention than life-threatening microvascular or macrovascular complications. Here, we review several diabetic musculoskeletal complications with a focus on the clinical importance of early recognition and management, which would improve quality of life and physical function.
