J Dent Rehabil Appl Sci.  2022 Jun;38(2):120-126. 10.14368/jdras.2022.38.2.120.

A treatment of drug resistant denture stomatitis by microbiological analysis and adjuvant therapy: a case report

• Song YG

• KMID: 2535013
• DOI: http://doi.org/10.14368/jdras.2022.38.2.120

Abstract

In severe cases of denture stomatitis, antifungal drugs are sometimes ineffective. This case is a 72-year-old patient who was prescribed fluconazole for five months but had no improvement in symptoms. After re-diagnosis, medication was performed, and temporary dentures were fabricated for oral rehabilitation. This report describes that microbiological analysis and adjuvant therapy can be helpful, in case does not improve symptoms even with continuous medication of antifungal agent.

Keyword

denture stomatitis; Candida albicans; microbiological analysis; probiotics

Figure

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  Fig. 1 Initial photographs. (A) Initial intra oral photographs, (B) Photographs of old denture.

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  Fig. 2 New temporary denture and soft liner with Diflucan.

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  Fig. 3 ERG11 and MDR-1 gene expression level of yeast and hyphae type of standard C. albicans and a sample from the patient using RT-PCR.

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  Fig. 4 Intra oral photographs. (A) Initial intra oral photographs, (B) Intraoral photograph of post treatment.

Reference

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