Ann Dermatol.  2022 Apr;34(2):87-94. 10.5021/ad.2022.34.2.87.

Association between Olfactory Receptors and Skin Physiology

Affiliations
  • 1Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Korea
  • 2Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, Korea
  • 3Department of Bio and Chemical Engineering, Hongik University, Sejong, Korea

Abstract

Olfactory receptors are chemosensory receptors that detect odorants and function in the initial perception of a smell. Intriguingly, olfactory receptors are also expressed in cells other than olfaction sensory cells, an expression pattern termed ectopic expression. Ectopically expressed olfactory receptors have a distinct role depending on the type of tissues or cells in which they are expressed. This review introduces current research on the ectopic expression and function of olfactory receptors in skin and provides insight into directions for future research.

Keyword

Ectopic gene expression; Olfactory receptor; Skin; Skin physiology
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