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COX-2 Inhibitor Use as an Early Treatment Option for Knee Osteoarthritis Patients in Korea: A Population-Based Cross-Sectional Study

Cho SK, Choi S, Kim H, Song YJ, Jung SY, Jang EJ, Sung YK

Background: To investigate the use of cyclooxygenase-2 (COX-2) inhibitors as an initial drug treatment for knee osteoarthritis (OA) patients. Methods: From 2013 to 2015, patients with knee OA were identified from...
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Association between Olfactory Receptors and Skin Physiology

Seo J, Choi S, Kim H, Park SH, Lee J

Olfactory receptors are chemosensory receptors that detect odorants and function in the initial perception of a smell. Intriguingly, olfactory receptors are also expressed in cells other than olfaction sensory cells,...
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Review of Inhalation Health Risks Involving Chloromethylisothiazolinone (CMIT) and Methylisothiazolinone (MIT) Used as Disinfectants in Household Humidifiers

Kim J, Kim J, Park S, Park S, Zoh KE, Zoh KE, Park J, Park J, Choi S, Choi S, Hwang SH, Hwang SH, Lee SY, Lee SY, Park DU, Park DU

The association between lung injury and exposure to humidifier disinfectant (HD) containing a mixture of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) has been controversial in South Korea. This study conducts a...
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Potential Utility of Fecal Calprotectin in Discriminating Colorectal Polyps From Other Major Etiologies in Children Presenting With Isolated Hematochezia

Kim YB, Kim JY, Choi S, Kim HJ, Lee YM, Lee Y, Jang HJ, Lee EH, Lee KJ, Kim SC, Choi SY, Kang Y, Yi DY, Choi YJ, Choe BH, Kang B

Background: Colorectal polyps are the most common cause of isolated hematochezia in children, which requires a colonoscopy for diagnosis. We aimed to investigate the potential utility of fecal calprotectin (FC)...
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The Effect of COVID–19 on Pediatric Intussusception: A Retrospective Study of a Single Center in South Korea with 10–Year Experience

Yoo YJ, Je BK, Choi GY, Lee JH, Choi S, Lee JY

Purpose To evaluate the effect of the emergence of coronavirus disease-19 (COVID-19) on pediatric intussusception. Materials and Methods Patients (< 18 years) who were diagnosed with intussusception and received enema reduction from 2011...
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Loss-of-function mutation in Pcsk1 increases serum APOA1 level and LCAT activity in mice

Khan AA, Kim N, Korstanje R, Choi S

Background: The convertase subtilisin/kexin family 1 gene (PCSK1) has been associated in various human genetics studies with a wide spectrum of metabolic phenotypes, including early-onset obesity, hyperphagia, diabetes insipidus, and...
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Guillain-Barre Syndrome After Two COVID-19 Vaccinations: Two Case Reports With Follow-up Electrodiagnostic Study

Kim JW, Kim YG, Park YC, Choi S, Lee S, Min HJ, Kim MJ

Guillain-Barre syndrome (GBS) is an immune-mediated acute polyradiculoneuropathy and commonly occurs after a preceding infection or immunization sequalae. Following the severe acute respiratory syndrome-coronavirus-2 virus pandemic with co-introduction of massive...
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Treatment of Human Immunodeficiency Virus-Associated Facial Lipoatrophy With Hyaluronic Acid Filler Mixed With Micronized Cross-Linked Acellular Dermal Matrix

Kim J, Song SY, Lee SG, Choi S, Lee YI, Choi JY, Lee JH

Background: Human immunodeficiency virus (HIV)-associated facial lipoatrophy (FLA) is a stigmatizing side effect associated with the use of highly active antiretroviral therapy. We sought to evaluate the safety and efficacy...
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Predicting Postoperative Complications and Long-Term Survival After Lung Cancer Surgery Using Eurolung Risk Score

Yun JK, Jeong JH, Lee GD, Kim HR, Kim YH, Kim DK, Park SI, Choi S

Background: This study aimed to assess the clinical relevance of the parsimonious Eurolung risk scoring system for predicting postoperative morbidity, mortality, and long-term survival in Korean patients with surgically resected...
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Lifestyle Modification in the Management of Metabolic Syndrome: Statement From Korean Society of CardioMetabolic Syndrome (KSCMS)

Kim HL, Chung J, Kim KJ, Kim HJ, Seo WW, Jeon KH, Cho I, Park JJ, Lee MH, Suh J, Lim SY, Choi S, Kim SH

With the recent rapid increase in obesity worldwide, metabolic syndrome (MetS) has gained significant importance. MetS is a cluster of obesity-related cardiovascular risk factors including abdominal obesity, atherogenic dyslipidemia, high...
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Analysis of Critical COVID-19 Cases Among Children in Korea

Lee H, Choi S, Park JY, Jo DS, Choi UY, Lee H, Jung YT, Chung IH, Choe YJ, Kim JY, Park YJ, Choi EH

Background: Coronavirus disease 2019 (COVID-19) is generally asymptomatic or mild in otherwise healthy children, however, severe cases may occur. In this study, we report the clinical characteristics of children classified...
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SARS-CoV-2 Delta Variant Breakthrough Infection and Onward Secondary Transmission in Household

Yi S, Kim JM, Choe YJ, Hong S, Choi S, Ahn SB, Kim M, Park YJ

Background: Despite the extraordinary speed of mass vaccination efforts, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant in a vaccinee with coronavirus disease 2019 (COVID-19) mRNA...
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Association between Fecal Calprotectin and Mucosal Healing in Pediatric Patients with Crohn’s Disease Who Have Achieved Sustained Clinical Remission with Anti-Tumor Necrosis Factor Agents

Lee YM, Choi S, Choe BH, Jang HJ, Kim S, Koh H, Kim ES, Kim MJ, Choe YH, Kang B

Background/Aims: Although mucosal healing (MH) is acknowledged as the treatment target in the treat-to-target era, there are limitations on repeated endoscopic examinations, especially in pediatric patients. We aimed to investigate...
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Signal Detection for Adverse Events of Finasteride Using Korea Adverse Event Reporting System (KAERS) Database

Baek JW, Yang BR, Choi S, Shin KH

To investigate signals of adverse drug reactions of finasteride by using the Korea Adverse Events Reporting System (KAERS) database. This pharmacovigilance was based on the database of the drug-related adverse...
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The Extract of Couroupita guianensis Aubl. Ameliorates Benign Prostatic Hyperplasia In Vitro and In Vivo

Kim YN, Kim NH, Souliya O, Uddin S, Lee SW, Kim SY, Choi S, Heo JD, Jeong EJ

The therapeutic effects of the leaves of Couroupita guianensis, a large tropical tree in the family of Lecythidaceae improving testosterone-induced Benign Prostatic Hyperplasia (BPH) were tested In Vitro and In...
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Importation and Transmission of SARS-CoV-2 B.1.1.529 (Omicron) Variant of Concern in Korea, November 2021

Lee JJ, Choe YJ, Jeong H, Kim M, Kim S, Yoo H, Park K, Kim C, Choi S, Sim J, Park Y, Huh IS, Hong G, Kim MY, Song JS, Lee J, Kim EJ, Rhee JE, Kim IH, Gwack J, Kim J, Jeon JH, Lee WG, Jeong S, Kim J, Bae B, Kim JE, Kim H, Lee HY, Lee SE, Kim JM, Park H, Yu M, Choi J, Kim J, Lee H, Jang EJ, Lim D, Lee S, Park YJ

In November 2021, 14 international travel-related severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant of concern (VOC) patients were detected in South Korea. Epidemiologic investigation revealed community transmission...
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A Randomized Controlled Trial for Doing vs. Omitting Intraoperative Frozen Section Biopsy for Resection Margin Status in Selected Patients Undergoing Breast-Conserving Surgery (OFF-MAP Trial)

Yoo TK, Kang YJ, Jeong J, Song JY, Kang SH, Lee HY, Kim ET, Yi O, Lee HB, Choi S, Park HS, Gwak G, Kim JI, Kim MK, Lee J, Kang HJ, Chae BJ

Purpose: Intraoperative frozen section biopsy is used to reduce the margin positive rate and re-excision rate and has been reported to have high diagnostic accuracy. A majority of breast surgeons...
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Experiences of Hospice and Palliative Nurses in Response to the COVID-19 Pandemic: A Qualitative Study

Kwon S, Choi S

Purpose: This study aimed to explore the experiences of hospice and palliative care (HPC) nurses at inpatient hospice centers in South Korea during the coronavirus disease 2019 pandemic. Methods: Data...
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Estimation of Lead Exposure Intensity by Industry Using Nationwide Exposure Databases in Korea

Koh DH, Park JH, Lee SG, Kim HC, Jung H, Kim I, Choi S, Park D

Background In a previous study, we estimated exposure prevalence and the number of workers exposed to carcinogens by industry in Korea. The present study aimed to evaluate the optimal exposure intensity...
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Assessment of early nutritional state in critical patients with intoxication and the effect of nutritional status on prognosis

Ko Dw, Choi S, Min Yg, Lee Hj, Park EJ

Purpose: Nutritional status and support in critically ill patients are important factors in determining patient recovery and prognosis. The aim of this study was to analyze the early nutritional status and...
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