J Korean Neurosurg Soc.  2021 Sep;64(5):808-817. 10.3340/jkns.2021.0012.

Factors Affecting Postoperative Complications and Outcomes of Cervical Spondylotic Myelopathy with Cerebral Palsy : A Retrospective Analysis

Affiliations
  • 1Department of Neurosurgery, Spine and Spinal Cord Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 2Department and Research Institute of Rehabilitation Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 3Graduate Program of NanoScience and Technology, Yonsei University College of Medicine, Seoul, Korea
  • 4Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea
  • 5Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea

Abstract


Objective
: Cervical surgery in patients with cervical spondylotic myelopathy (CSM) and cerebral palsy (CP) is challenging owing to the complexities of the deformity. We assessed factors affecting postoperative complications and outcomes after CSM surgery in patients with CP.
Methods
: Thirty-five consecutive patients with CP and CSM who underwent cervical operations between January 2006 and January 2014 were matched to 35 non-cerebral palsy (NCP) control patients. Postoperative complications and radiologic outcomes were compared between the groups. In the CP group, the Japanese Orthopaedic Association score; Oswestry neck disability index; modified Barthel index; and values for the grip and pinch, Box and Block, and Jebsen-Taylor hand function tests were obtained preand postoperatively and compared between those with and without postoperative complications.
Results
: Sixteen patients (16/35%) in the CP group and seven (7/35%) in the NCP group (p=0.021) had postoperative complications. Adjacent segment degeneration (p=0.021), postoperative motor weakness (p=0.037), and revisions (p=0.003) were significantly more frequent in the CP group than in the NCP group; however, instrument-related complications were not significantly higher in the CP group (7/35 vs. 5/35, p=0.280). The number of preoperative fixed cervical deformities were significantly higher in CP with postoperative complications (5/16 vs. 1/19, p=0.037). In the CP group, clinical outcomes were almost similar between those with and without postoperative complications.
Conclusion
: The occurrence of complications during the follow-up period was high in patients with CP. However, postoperative complications did not significantly affect clinical outcomes.

Keyword

Cervical spondylotic myelopathy; Cerebral palsy; Postoperative complications; Kyhposis; Pseudoarthrosis

Reference

References

1. Anderson WW, Wise BL, Itabashi HH, Jones M. Cervical spondylosis in patients with athetosis. Neurology. 12:410–412. 1962.
Article
2. Azuma S, Seichi A, Ohnishi I, Kawaguchi H, Kitagawa T, Nakamura K. Long-term results of operative treatment for cervical spondylotic myelopathy in patients with athetoid cerebral palsy: an over 10-year follow-up study. Spine (Phila Pa 1976). 27:943–948. discussion 948. 2002.
Article
3. Demura S, Kato S, Shinmura K, Yokogawa N, Yonezawa N, Shimizu T, et al. More than 10-year follow-up after laminoplasty and pedicle screw fixation for cervical myelopathy associated with athetoid cerebral palsy. Spine (Phila Pa 1976). 45:727–734. 2020.
Article
4. Demura S, Murakami H, Kawahara N, Kato S, Yoshioka K, Tsuchiya H. Laminoplasty and pedicle screw fixation for cervical myelopathy associated with athetoid cerebral palsy: minimum 5-year follow-up. Spine (Phila Pa 1976). 38:1764–1769. 2013.
Article
5. Fuji T, Yonenobu K, Fujiwara K, Yamashita K, Ebara S, Ono K, et al. Cervical radiculopathy or myelopathy secondary to athetoid cerebral palsy. J Bone Joint Surg Am. 69:815–821. 1987.
Article
6. Harada T, Ebara S, Anwar MM, Okawa A, Kajiura I, Hiroshima K. The cervical spine in athetoid cerebral palsy. A radiological study of 180 patients. J Bone Joint Surg Br. 78:613–619. 1996.
7. Hartmann S, Thomé C, Abramovic A, Lener S, Schmoelz W, Koller J, et al. The effect of rod pattern, outrigger, and multiple screw-rod constructs for surgical stabilization of the 3-column destabilized cervical spine - a biomechanical analysis and introduction of a novel technique. Neurospine. 17:610–629. 2020.
Article
8. Hasler CC. Operative treatment for spinal deformities in cerebral palsy. J Child Orthop. 7:419–423. 2013.
Article
9. Jameson R, Rech C, Garreau de Loubresse C. Cervical myelopathy in athetoid and dystonic cerebral palsy: retrospective study and literature review. Eur Spine J. 19:706–712. 2010.
Article
10. Kidron D, Steiner I, Melamed E. Late-onset progressive radiculomyelopathy in patients with cervical athetoid-dystonic cerebral palsy. Eur Neurol. 27:164–166. 1987.
Article
11. Kim CW, Hyun SJ, Kim KJ. Surgical impact on global sagittal alignment and health-related quality of life following cervical kyphosis correction surgery: systematic review. Neurospine. 17:497–504. 2020.
Article
12. Kim KN, Ahn PG, Ryu MJ, Shin DA, Yi S, Yoon DH, et al. Long-term surgical outcomes of cervical myelopathy with athetoid cerebral palsy. Eur Spine J. 23:1464–1471. 2014.
Article
13. Lau D, Ames CP. Three-column osteotomy for the treatment of rigid cervical deformity. Neurospine. 17:525–533. 2020.
Article
14. Lee CK, Shin DA, Yi S, Kim KN, Shin HC, Yoon DH, et al. Correlation between cervical spine sagittal alignment and clinical outcome after cervical laminoplasty for ossification of the posterior longitudinal ligament. J Neurosurg Spine. 24:100–107. 2016.
Article
15. Lee JJ, Oh SH, Jeong YH, Park SM, Jeon HS, Kim HC, et al. Surgical strategies for cervical deformities associated with neuromuscular disorders. Neurospine. 17:513–524. 2020.
Article
16. Lee YJ, Chung DS, Kim JT, Bong HJ, Han YM, Park YS. Surgical treatments for cervical spondylotic myelopathy associated with athetoid cerebral palsy. J Korean Neurosurg Soc. 43:294–299. 2008.
Article
17. Master DL, Son-Hing JP, Poe-Kochert C, Armstrong DG, Thompson GH. Risk factors for major complications after surgery for neuromuscular scoliosis. Spine (Phila Pa 1976). 36:564–571. 2011.
Article
18. McCluer S. Cervical spondylosis with myelopathy as a complication of cerebral palsy. Paraplegia. 20:308–312. 1982.
Article
19. Nishihara N, Tanabe G, Nakahara S, Imai T, Murakawa H. Surgical treatment of cervical spondylotic myelopathy complicating athetoid cerebral palsy. J Bone Joint Surg Br. 66:504–508. 1984.
Article
20. Piazzolla A, Solarino G, De Giorgi S, Mori CM, Moretti L, De Giorgi G. Cotrel-Dubousset instrumentation in neuromuscular scoliosis. Eur Spine J 20 Suppl. 1:S75–S84. 2011.
Article
21. Polk JL, Maragos VA, Nicholas JJ. Cervical spondylotic myeloradiculopathy in dystonia. Arch Phys Med Rehabil. 73:389–392. 1992.
Article
22. Pollard CA. Preliminary validity study of the pain disability index. Percept Mot Skills. 59:974. 1984.
Article
23. Rumalla K, Yarbrough CK, Pugely AJ, Koester L, Dorward IG. Spinal fusion for pediatric neuromuscular scoliosis: national trends, complications, and in-hospital outcomes. J Neurosurg Spine. 25:500–508. 2016.
Article
24. Samdani AF, Belin EJ, Bennett JT, Miyanji F, Pahys JM, Shah SA, et al. Major perioperative complications after spine surgery in patients with cerebral palsy: assessment of risk factors. Eur Spine J. 25:795–800. 2016.
Article
25. Scheer JK, Tang JA, Smith JS, Acosta FL Jr, Protopsaltis TS, Blondel B, et al. Cervical spine alignment, sagittal deformity, and clinical implications: a review. J Neurosurg Spine. 19:141–159. 2013.
26. Sharma S, Wu C, Andersen T, Wang Y, Hansen ES, Bünger CE. Prevalence of complications in neuromuscular scoliosis surgery: a literature meta-analysis from the past 15 years. Eur Spine J. 22:1230–1249. 2013.
Article
27. Shimokawa N, Sato H, Matsumoto H, Takami T. Complex revision surgery for cervical deformity or implant failure. Neurospine. 17:543–553. 2020.
Article
28. Vialle R, Thévenin-Lemoine C, Mary P. Neuromuscular scoliosis. Orthop Traumatol Surg Res. 99:S124–S139. 2013.
Article
29. Watanabe K, Hirano T, Katsumi K, Ohashi M, Shoji H, Yamazaki A, et al. Surgical outcomes of posterior spinal fusion alone using cervical pedicle screw constructs for cervical disorders associated with athetoid cerebral palsy. Spine (Phila Pa 1976). 42:1835–1843. 2017.
Article
30. Watanabe K, Otani K, Nikaido T, Kato K, Kobayashi H, Yabuki S, et al. Surgical outcomes of cervical myelopathy in patients with athetoid cerebral palsy: a 5-year follow-up. Asian Spine. J11:928–934. 2017.
Article
31. Wewel JT, Brahimaj BC, Kasliwal MK, Traynelis VC. Perioperative complications with multilevel anterior and posterior cervical decompression and fusion. J Neurosurg Spine. 20:1–6. 2019.
Article
32. Wong AS, Massicotte EM, Fehlings MG. Surgical treatment of cervical myeloradiculopathy associated with movement disorders: indications, technique, and clinical outcome. J Spinal Disord Tech. 18 Suppl:S107–S114. 2005.
33. Yaszay B, Bartley CE, Sponseller PD, Abel M, Cahill PJ, Shah SA, et al. Major complications following surgical correction of spine deformity in 257 patients with cerebral palsy. Spine Deform. 8:1305–1312. 2020.
Article
34. Yonenobu K, Okada K, Fuji T, Fujiwara K, Yamashita K, Ono K. Causes of neurologic deterioration following surgical treatment of cervical myelopathy. Spine (Phila Pa 1976). 11:818–823. 1986.
Article
Full Text Links
  • JKNS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr