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Differential Expression of NME4 in Trophoblast Stem-Like Cells and Peripheral Blood Mononuclear Cells of Normal Pregnancy and Preeclampsia

Yu JH, Jung YJ, Kim MS, Cho SR, Kim YH

Background: Preeclampsia (PE) is known to arise from insufficient trophoblast invasion as uterine spiral arteries lack remodeling. A significant reduction in placental perfusion induces an ischemic placental microenvironment due to...
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Factors Affecting Postoperative Complications and Outcomes of Cervical Spondylotic Myelopathy with Cerebral Palsy : A Retrospective Analysis

Kim HC, Jeon H, Jeong YH, Park S, An SB, Heo JH, Shin DA, Yi S, Kim KN, Ha Y, Cho SR

Objective : Cervical surgery in patients with cervical spondylotic myelopathy (CSM) and cerebral palsy (CP) is challenging owing to the complexities of the deformity. We assessed factors affecting postoperative complications...
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The laboratory test procedure to confirm rotavirus vaccine infection in severe complex immunodeficiency patients

Chae SJ, Cho SR, Choi W, Han MG, Lee DY

The rotavirus vaccine is a live vaccine, and there is a possibility of infection by the virus strain used in the vaccine. We investigated the process of determining whether an...
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Pelizaeus-Merzbacher Disease with PLP1 Exon 1 Duplication, Previously Misdiagnosed as Cerebral Palsy: a Case Report

Lee SJ, Kim TY, Hong S, Byun J, Cho SR

Pelizaeus-Merzbacher disease (PMD) is a X-linked recessive disorder with dysmyelination in central nervous system caused by proteolipid protein 1 (PLP1) gene mutation. We report a case of PMD with PLP1...
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Development of Risk Management Examples for Korean Clinical Laboratories

Kim S, Kim KH, Cho SR, Ahn J, Lee WI

Background: Risk management is one of the quality management efforts to provide the best medical services, but the concept is still unfamiliar to clinical laboratories in Korea. Risk management-related checklists...
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Outbreak associated with Rotavirus G11,P[25] in Korea in 2018

Chae SJ, Jung S, Cho SR, Choi W, Lee DY

We here report the first outbreak caused by rotavirus G11,P[25] in Korea in 2018, representing a case of re-assortment with pig-derived rotavirus. The genotype constellation was identical to the virus...
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A Case of Preleukemic Chronic Myeloid Leukemia Following Chemotherapy and Autologous Transplantation for T-lymphoblastic Lymphoma

Choi H, Cho Sr, Yang D, Lee W, Hwang H, Lee HS, Kim DJ, Kim T, Kim MH

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An Outbreak Associated with Sapovirus GI.3 in an Elementary School in Gyeonggi-do, Korea

Cho SR, Yun SJ, Chae SJ, Jung S, Kim JH, Yong KC, Cho EH, Choi W, Lee DY

On October 4, 2018, an outbreak of gastroenteritis associated with sapovirus occurred among elementary school students in Gyeonggi-do, Korea. Epidemiologic studies were conducted in a retrospective cohort approach. Using self-administered...
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Juvenile Parkinsonism with PARK2 Gene Mutation Misdiagnosed as Dopa-responsive Dystonia: a Case Report

Hong S, Lee S, Cho SR

Parkinson's disease is prevalent in elderly patients, usually aged over 50 years. If clinical symptoms of parkinsonism appear before 21 years of age, it is called juvenile parkinsonism (JP). JP...
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Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea

Kim JM, Kim HM, Lee EJ, Jo HJ, Yoon Y, Lee NJ, Son J, Lee YJ, Kim MS, Lee YP, Chae SJ, Park KR, Cho SR, Park S, Kim SJ, Wang E, Woo S, Lim A, Park SJ, Jang J, Chung YS, Chin BS, Lee JS, Lim D, Han MG, Yoo CK

Objectives Coronavirus Disease-19 (COVID-19) is a respiratory infection characterized by the main symptoms of pneumonia and fever. It is caused by the novel coronavirus severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), which...
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Korean Clinical Laboratory Accreditation Program Quality Standards for Laboratory Management: Identifying a Compliance Gap with World Health Organization Quality System Essentials

Jeon BR, Yoon C, Jang MA, Cho SR, Kim S, Lee YK

Background The Laboratory Medicine Foundation (LMF) checklists explain the accreditation requirements of the program and reflect quality standards like those of the Clinical Laboratory Standards Institute (CLSI) or quality system essentials...
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Chromosomal Deletion in 7q31.2-31.32 Involving Ca2⁺-Dependent Activator Protein for Secretion Gene in a Patient with Cerebellar Ataxia: a Case Report

Hong S, Lee SJ, Cho SR

We present a 33-year-old male patient with cerebellar ataxia. He was first considered to have a psychiatric conversion disorder but finally found to have chromosomal deletion in 7q31.2-31.32 involving Ca2⁺-dependent...
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Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report

Chae M, Hong S, Jung NY, Chang WS, Cho SR

Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known...
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Cell Surface Antigen Display for Neuronal Differentiation-Specific Tracking

Kim SC, Lee EH, Yu JH, Kim SM, Nam BG, Chung HY, Kim YS, Cho SR, Park CH

Cell therapeutic agents for treating degenerative brain diseases using neural stem cells are actively being developed. However, few systems have been developed to monitor in real time whether the transplanted...
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First Case of Plasma Cell Myeloma With Brown Tumor Features Unrelated to Hyperparathyroidism

Kim H, Kim K, Cho SR, Kim HJ, Kim SH

No abstract available.
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The 2016 WHO versus 2008 WHO Criteria for the Diagnosis of Chronic Myelomonocytic Leukemia

Moon Y, Kim MH, Kim HR, Ahn JY, Huh J, Huh JY, Han JH, Park JS, Cho SR

The 2016 WHO diagnostic criteria for chronic myelomonocytic leukemia (CMML) require both absolute and relative monocytosis (≥1×10⁹/L and ≥10% of white blood cell counts) in peripheral blood. Moreover, myeloproliferative neoplasm...
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Pseudo-Chediak-Higashi granules in myeloid cells in therapy-related AML with RUNX1-RUNX1T1

Cho SR, Park JS

No abstract available.
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Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis

Ahn JY, Song JE, Ann HW, Jeon Y, Ahn MY, Jung IY, Kim MH, Jeong W, Jeong SJ, Ku NS, Kim JM, Na S, Cho SR, Choi JY

PURPOSE: Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improve functional impairment are important. We assessed the effects of early exercise...
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Relationship Between Swallowing Function and Maximum Phonation Time in Patients With Parkinsonism

Ko EJ, Chae M, Cho SR

OBJECTIVE: To identify the relationship between maximum phonation time (MPT) and swallowing function, as well as the elements of swallowing, in order to provide a rationale for speech therapy in...
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Cellular Hemoglobin Is a Useful Alternative Parameter when Lipemia Interferes with Hemoglobin Measurement

Choi BH, Cho SR, Park IJ

BACKGROUND: Saline replacement is a difficult and time-consuming procedure employed to measure hemoglobin (Hb) levels when lipaemia interferes with the accurate determination of Hb content. As an alternative method, we...
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