Ann Rehabil Med.  2021 Jun;45(3):225-259. 10.5535/arm.21110.

Clinical Practice Guideline for Postoperative Rehabilitation in Older Patients With Hip Fractures

Affiliations
  • 1Department of Rehabilitation Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea
  • 2Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
  • 3Department of Physical Medicine and Rehabilitation, Anam Hospital, Korea University College of Medicine, Seoul, Korea
  • 4Department of Rehabilitation Medicine, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea
  • 5Department of Rehabilitation Medicine, Seoul National University Hospital, National Traffic Injury Rehabilitation Hospital, Yangpyeong, Korea
  • 6Namdarun Rehabilitation Clinic, Yongin, Korea
  • 7Department of Physical Medicine and Rehabilitation, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
  • 8Department of Rehabilitation Medicine, Yeouido Saint Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
  • 9Physical Therapy, Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
  • 10Department of Rehabilitation Medicine, Chungbuk National University College of Medicine, Chungbuk National University Hospital, Cheongju, Korea
  • 11Department of Orthopaedic Surgery, Daejeon Eulji Medical Center, Eulji University School of Medicine, Daejeon, Korea
  • 12Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea
  • 13Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
  • 14Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 15Department of Physical Medicine and Rehabilitation, Veterans Health Service Medical Center, Seoul, Korea
  • 16Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School & Hospital, Gwangju, Korea
  • 17Division of Geriatrics, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 18Department of Food and Nutrition Services, Hanyang University Hospital, Seoul, Korea
  • 19Department of Physical Medicine and Rehabilitation, Kyung Hee University Hospital at Gangdong, Seoul, Korea
  • 20Department of Physical Medicine and Rehabilitation, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
  • 21Howareyou Rehabilitation Clinic, Seoul, Korea
  • 22Department of Physical Therapy, Eulji University, Seongnam, Korea
  • 23Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 24Department of Physical Medicine and Rehabilitation, Myongji Hospital, Goyang, Korea
  • 25Nutrition Team, Kyung Hee University Medical Center, Seoul, Korea
  • 26Department of Rehabilitation Medicine, Konkuk University School of Medicine and Konkuk University Medical Center, Seoul, Korea
  • 27Department of Rehabilitation Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea
  • 28Department of Physical Medicine and Rehabilitation, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
  • 29Department of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
  • 30Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
  • 31Department of Rehabilitation Medicine, Gangnam Severance Hospital, Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea
  • 32Department of Nursing, Konkuk University, Chungju, Korea
  • 33Department of Food and Nutrition, Hanyang University, Seoul, Korea
  • 34Occupational Therapy, Department of Rehabilitation Medicine, Asan Medical Center, Seoul, Korea
  • 35Department of Rehabilitation Medicine, Ewha Woman’s University Seoul Hospital, Ewha Womans University School of Medicine, Seoul, Korea
  • 36Department of Rehabilitation Medicine, Research Institute and Hospital, National Cancer Center, Goyang, Korea
  • 37Department of Orthopaedic Surgery, Gyeongsang National University Hospital, Jinju, Korea

Abstract


Objective
The incidence of hip fractures is increasing worldwide with the aging population, causing a challenge to healthcare systems due to the associated morbidities and high risk of mortality. After hip fractures in frail geriatric patients, existing comorbidities worsen and new complications are prone to occur. Comprehensive rehabilitation is essential for promoting physical function recovery and minimizing complications, which can be achieved through a multidisciplinary approach. Recommendations are required to assist healthcare providers in making decisions on rehabilitation post-surgery. Clinical practice guidelines regarding rehabilitation (physical and occupational therapies) and management of comorbidities/complications in the postoperative phase of hip fractures have not been developed. This guideline aimed to provide evidence-based recommendations for various treatment items required for proper recovery after hip fracture surgeries. Methods Reflecting the complex perspectives associated with rehabilitation post-hip surgeries, 15 key questions (KQs) reflecting the complex perspectives associated with post-hip surgery rehabilitation were categorized into four areas: multidisciplinary, rehabilitation, community-care, and comorbidities/complications. Relevant literature from four databases (PubMed, EMBASE, Cochrane Library, and KoreaMed) was searched for articles published up to February 2020. The evidence level and recommended grade were determined according to the grade of recommendation assessment, development, and evaluation method. Results A multidisciplinary approach, progressive resistance exercises, and balance training are strongly recommended. Early ambulation, weigh-bearing exercises, activities of daily living training, community-level rehabilitation, management of comorbidities/complication prevention, and nutritional support were also suggested. This multidisciplinary approach reduced the total healthcare cost.
Conclusion
This guideline presents comprehensive recommendations for the rehabilitation of adult patients after hip fracture surgery.

Keyword

Hip fractures; Practice Guideline; Rehabilitation; Patient Care Team; Community Health Services

Reference

1. Lee YK, Kim JW, Lee MH, Moon KH, Koo KH. Trend in the age-adjusted incidence of hip fractures in South Korea: systematic review. Clin Orthop Surg. 2017; 9:420–3.
Article
2. Gullberg B, Johnell O, Kanis JA. World-wide projections for hip fracture. Osteoporos Int. 1997; 7:407–13.
Article
3. Kang HY, Yang KH, Kim YN, Moon SH, Choi WJ, Kang DR, et al. Incidence and mortality of hip fracture among the elderly population in South Korea: a population-based study using the national health insurance claims data. BMC Public Health. 2010; 10:230.
Article
4. Zuckerman JD. Hip fracture. N Engl J Med. 1996; 334:1519–25.
Article
5. Mears SC. Classification and surgical approaches to hip fractures for nonsurgeons. Clin Geriatr Med. 2014; 30:229–41.
Article
6. Fox KM, Magaziner J, Hebel JR, Kenzora JE, Kashner TM. Intertrochanteric versus femoral neck hip fractures: differential characteristics, treatment, and sequelae. J Gerontol A Biol Sci Med Sci. 1999; 54:M635–40.
Article
7. Kanis JA, Johnell O. The burden of osteoporosis. J Endocrinol Invest. 1999; 22:583–8.
Article
8. Nikitovic M, Wodchis WP, Krahn MD, Cadarette SM. Direct health-care costs attributed to hip fractures among seniors: a matched cohort study. Osteoporos Int. 2013; 24:659–69.
Article
9. Nightingale EJ, Sturnieks D, Sherrington C, Moseley AM, Cameron ID, Lord SR. Impaired weight transfer persists at least four months after hip fracture and rehabilitation. Clin Rehabil. 2010; 24:565–73.
Article
10. Braithwaite RS, Col NF, Wong JB. Estimating hip fracture morbidity, mortality and costs. J Am Geriatr Soc. 2003; 51:364–70.
Article
11. Magaziner J, Lydick E, Hawkes W, Fox KM, Zimmerman SI, Epstein RS, et al. Excess mortality attributable to hip fracture in white women aged 70 years and older. Am J Public Health. 1997; 87:1630–6.
Article
12. Tedesco D, Gibertoni D, Rucci P, Hernandez-Boussard T, Rosa S, Bianciardi L, et al. Impact of rehabilitation on mortality and readmissions after surgery for hip fracture. BMC Health Serv Res. 2018; 18:701.
Article
13. Foss NB, Kehlet H. Mortality analysis in hip fracture patients: implications for design of future outcome trials. Br J Anaesth. 2005; 94:24–9.
Article
14. Cheng SY, Levy AR, Lefaivre KA, Guy P, Kuramoto L, Sobolev B. Geographic trends in incidence of hip fractures: a comprehensive literature review. Osteoporos Int. 2011; 22:2575–86.
Article
15. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007; 22:465–75.
Article
16. Chudyk AM, Jutai JW, Petrella RJ, Speechley M. Systematic review of hip fracture rehabilitation practices in the elderly. Arch Phys Med Rehabil. 2009; 90:246–62.
Article
17. National Institute for Health and Care Excellence. Hip fracture: management 2017 [Internet]. London, UK: National Institute for Health and Care Excellence;c2021. [cited 2021 May 24]. Available from: https://www.nice.org.uk/guidance/cg124.
18. British Orthopaedic Association. The care of patients with fragility fracture [Internet]. London, UK: British Orthopaedic Association;2007. [cited 2021 May 24]. Available from: https://www.bgs.org.uk/sites/default/files/content/attachment/2018-05-02/Blue%20Book%20on%20fragility%20fracture%20care.pdf.
19. Scottish Intercollegiate Guidelines Network. Management of hip fracture in older people: a national clinical guideline [Internet]. Edinburgh, Scotland: Scottish Intercollegiate Guidelines Network;2009. [cited 2021 May 24]. Available from: https://pdf4pro.com/cdn/part-of-nhs-quality-improvement-scotland-2531e4.pdf.
20. Scottish Committee for Orthopaedics and Trauma; Royal College of Emergency Medicine National Board for Scotland; British Geriatrics Society. Scottish Standards of care for hip fracture patients 2018 [Internet]. Edinburgh, Scotland: NHS Scotland;c2019. [cited 2021 May 24]. Available from: https://www.shfa.scot.nhs.uk/_docs/2018/Scottish-standards-of-care-for-hip-fracture-patients-2018.pdf.
21. Australian and New Zealand Hip Fracture Registry. Australian and New Zealand Guideline for hip fracture care [Internet]. Sydney: Australian and New Zealand Hip Fracture Registry Steering Group;2014. [cited 2021 May 24]. Available from: https://anzhfr.org/wp-content/uploads/2016/07/ANZ-Guideline-for-Hip-Fracture-Care.pdf.
22. Mak JC, Cameron ID, March LM; National Health and Medical Research Council. Evidence-based guidelines for the management of hip fractures in older persons: an update. Med J Aust. 2010; 192:37–41.
Article
23. Agency for Healthcare Research and Quality. Treatment of common hip fractures (AHRQ Publication No. 09-E013) [Internet]. Rockville, MD: Agency for Healthcare Research and Quality;2009. [cited 2021 May 24]. Available from: https://www.ahrq.gov/downloads/pub/evidence/pdf/hipfracture/hipfracture.pdf.
24. McDonough CM, Harris-Hayes M, Kristensen MT, Overgaard JA, Herring TB, Kenny AM, et al. Physical therapy management of older adults with hip fracture. J Orthop Sports Phys Ther. 2021; 51:CPG1–81.
Article
25. Yoo JI, Lee YK, Koo KH, Park YJ, Ha YC. Concerns for older adult patients with acute hip fracture. Yonsei Med J. 2018; 59:1240–4.
Article
26. Saltvedt I, Prestmo A, Einarsen E, Johnsen LG, Helbostad JL, Sletvold O. Development and delivery of patient treatment in the Trondheim Hip Fracture Trial: a new geriatric in-hospital pathway for elderly patients with hip fracture. BMC Res Notes. 2012; 5:355.
Article
27. Hutchings L, Fox R, Chesser T. Proximal femoral fractures in the elderly: how are we measuring outcome? Injury. 2011; 42:1205–13.
Article
28. Scottish Intercollegiate Guidelines Network. Risk reduction and management of delirium: a national clinical guideline. Edinburgh, Scotland: Scottish Intercollegiate Guidelines Network;2019.
29. Falck-Ytter Y, Francis CW, Johanson NA, Curley C, Dahl OE, Schulman S, et al. Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141(2 Suppl):e278S325S.
30. Bang SM, Jang MJ, Kim KH, Yhim HY, Kim YK, Nam SH, et al. Prevention of venous thromboembolism, 2nd edition: Korean Society of Thrombosis and Hemostasis Evidence-based Clinical Practice Guidelines. J Korean Med Sci. 2014; 29:164–71.
Article
31. Kim SY, Park JE, Lee YJ, Seo HJ, Sheen SS, Hahn S, et al. Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity. J Clin Epidemiol. 2013; 66:408–14.
Article
32. Higgins JP, Thomas J. Cochrane handbook for systematic reviews of interventions. London, UK: Cochrane Collaboration;2021.
33. Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or nonrandomised studies of healthcare interventions, or both. BMJ. 2017; 358:j4008.
Article
34. The Grading of Recommendations Assessment. Development and Evaluation (GRADE) working group [Internet]. London, UK: The GRADE Working Group;c2021. [cited 2021 May 24]. Available from: www.gradeworkinggroup.org.
35. Murad MH, Montori VM, Ioannidis JP, Jaeschke R, Devereaux PJ, Prasad K, et al. How to read a systematic review and meta-analysis and apply the results to patient care: users’ guides to the medical literature. JAMA. 2014; 312:171–9.
36. Pollock A, Farmer SE, Brady MC, Langhorne P, Mead GE, Mehrholz J, et al. An algorithm was developed to assign GRADE levels of evidence to comparisons within systematic reviews. J Clin Epidemiol. 2016; 70:106–10.
Article
37. Oh MK, Jo H, Lee YK. Improving the reliability of clinical practice guideline appraisals: effects of the Korean AGREE II scoring guide. J Korean Med Sci. 2014; 29:771–5.
Article
38. Farrow L, Hall A, Wood AD, Smith R, James K, Holt G, et al. Quality of care in hip fracture patients: the relationship between adherence to national standards and improved outcomes. J Bone Joint Surg Am. 2018; 100:751–7.
39. Bonanni S, Sorensen AA, Dubin J, Drees B. The role of the fracture liaison service in osteoporosis care. Mo Med. 2017; 114:295–8.
40. McLellan AR, Gallacher SJ, Fraser M, McQuillian C. The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture. Osteoporos Int. 2003; 14:1028–34.
Article
41. Dreinhofer KE, Mitchell PJ, Begue T, Cooper C, Costa ML, Falaschi P, et al. A global call to action to improve the care of people with fragility fractures. Injury. 2018; 49:1393–7.
Article
42. Adunsky A, Levenkrohn S, Fleissig Y, Arad M, Heruti RJ. Rehabilitation outcomes in patients with full weight-bearing hip fractures. Arch Gerontol Geriatr. 2001; 33:123–31.
Article
43. Flikweert ER, Wendt KW, Diercks RL, Izaks GJ, Landsheer D, Stevens M, et al. Complications after hip fracture surgery: are they preventable? Eur J Trauma Emerg Surg. 2018; 44:573–80.
Article
44. Adunsky A, Arad M, Levi R, Blankstein A, Zeilig G, Mizrachi E. Five-year experience with the ‘Sheba’ model of comprehensive orthogeriatric care for elderly hip fracture patients. Disabil Rehabil. 2005; 27:1123–7.
Article
45. Pioli G, Bendini C, Pignedoli P, Giusti A, Marsh D. Orthogeriatric co-management: managing frailty as well as fragility. Injury. 2018; 49:1398–402.
46. Thingstad P, Taraldsen K, Saltvedt I, Sletvold O, Vereijken B, Lamb SE, et al. The long-term effect of comprehensive geriatric care on gait after hip fracture: the Trondheim Hip Fracture Trial: a randomised controlled trial. Osteoporos Int. 2016; 27:933–42.
47. Kammerlander C, Roth T, Friedman SM, Suhm N, Luger TJ, Kammerlander-Knauer U, et al. Ortho-geriatric service: a literature review comparing different models. Osteoporos Int. 2010; 21(Suppl 4):S637–46.
48. Giusti A, Barone A, Razzano M, Pizzonia M, Pioli G. Optimal setting and care organization in the management of older adults with hip fracture. Eur J Phys Rehabil Med. 2011; 47:281–96.
49. Nordstrom P, Thorngren KG, Hommel A, Ziden L, Anttila S. Effects of geriatric team rehabilitation after hip fracture: meta-analysis of randomized controlled trials. J Am Med Dir Assoc. 2018; 19:840–5.
50. Bachmann S, Finger C, Huss A, Egger M, Stuck AE, Clough-Gorr KM. Inpatient rehabilitation specifically designed for geriatric patients: systematic review and meta-analysis of randomised controlled trials. BMJ. 2010; 340:c1718.
Article
51. Halbert J, Crotty M, Whitehead C, Cameron I, Kurrle S, Graham S, et al. Multi-disciplinary rehabilitation after hip fracture is associated with improved outcome: a systematic review. J Rehabil Med. 2007; 39:507–12.
Article
52. Handoll HH, Cameron ID, Mak JC, Finnegan TP. Multidisciplinary rehabilitation for older people with hip fractures. Cochrane Database Syst Rev. 2009; (4):CD007125.
Article
53. Chilov MN, Cameron ID, March LM; Australian National Health and Medical Research Council. Evidence-based guidelines for fixing broken hips: an update. Med J Aust. 2003; 179:489–93.
Article
54. Oldmeadow LB, Edwards ER, Kimmel LA, Kipen E, Robertson VJ, Bailey MJ. No rest for the wounded: early ambulation after hip surgery accelerates recovery. ANZ J Surg. 2006; 76:607–11.
Article
55. Su B, Newson R, Soljak H, Soljak M. Associations between post-operative rehabilitation of hip fracture and outcomes: national database analysis (90 characters). BMC Musculoskelet Disord. 2018; 19:211.
Article
56. Frenkel Rutenberg T, Vitenberg M, Haviv B, Velkes S. Timing of physiotherapy following fragility hip fracture: delays cost lives. Arch Orthop Trauma Surg. 2018; 138:1519–24.
Article
57. Kuru T, Olcar HA. Effects of early mobilization and weight bearing on postoperative walking ability and pain in geriatric patients operated due to hip fracture: a retrospective analysis. Turk J Med Sci. 2020; 50:117–25.
Article
58. Pioli G, Frondini C, Lauretani F, Davoli ML, Pellicciotti F, Martini E, et al. Time to surgery and rehabilitation resources affect outcomes in orthogeriatric units. Arch Gerontol Geriatr. 2012; 55:316–22.
Article
59. Kamel HK, Iqbal MA, Mogallapu R, Maas D, Hoffmann RG. Time to ambulation after hip fracture surgery: relation to hospitalization outcomes. J Gerontol A Biol Sci Med Sci. 2003; 58:1042–5.
Article
60. Taylor NF, Dodd KJ, Damiano DL. Progressive resistance exercise in physical therapy: a summary of systematic reviews. Phys Ther. 2005; 85:1208–23.
Article
61. Aarden JJ, van der Schaaf M, van der Esch M, Reichardt LA, van Seben R, Bosch JA, et al. Muscle strength is longitudinally associated with mobility among older adults after acute hospitalization: the Hospital-ADL study. PLoS One. 2019; 14:e0219041.
Article
62. Roy MA, Doherty TJ. Reliability of hand-held dynamometry in assessment of knee extensor strength after hip fracture. Am J Phys Med Rehabil. 2004; 83:813–8.
Article
63. Delorme TL, Watkins AL. Technics of progressive resistance exercise. Arch Phys Med Rehabil. 1948; 29:263–73.
64. Deschenes MR. General principles of exercise prescription. In : Riebe D, editor. ACSM’s Guidelines for Exercise Testing and Prescription. 10th ed. Philadelphia, PA: Wolters Kluwer;2018. p. 143–74.
65. Lee SY, Yoon BH, Beom J, Ha YC, Lim JY. Effect of lower-limb progressive resistance exercise after hip fracture surgery: a systematic review and meta-analysis of randomized controlled studies. J Am Med Dir Assoc. 2017; 18:1096.e19–1096.e26.
Article
66. Stasi S, Papathanasiou G, Chronopoulos E, Dontas IA, Baltopoulos IP, Papaioannou NA. The effect of intensive abductor strengthening on postoperative muscle efficiency and functional ability of hip-fractured patients: a randomized controlled trial. Indian J Orthop. 2019; 53:407–19.
67. Kronborg L, Bandholm T, Palm H, Kehlet H, Kristensen MT. Effectiveness of acute in-hospital physiotherapy with knee-extension strength training in reducing strength deficits in patients with a hip fracture: a randomised controlled trial. PLoS One. 2017; 12:e0179867.
Article
68. Koval KJ, Sala DA, Kummer FJ, Zuckerman JD. Postoperative weight-bearing after a fracture of the femoral neck or an intertrochanteric fracture. J Bone Joint Surg Am. 1998; 80:352–6.
Article
69. Wu J, Kurrle S, Cameron ID. Restricted weight bearing after hip fracture surgery in the elderly: economic costs and health outcomes. J Eval Clin Pract. 2009; 15:217–9.
Article
70. Koval KJ, Friend KD, Aharonoff GB, Zukerman JD. Weight bearing after hip fracture: a prospective series of 596 geriatric hip fracture patients. J Orthop Trauma. 1996; 10:526–30.
Article
71. Bhandari M, Swiontkowski M. Management of acute hip fracture. N Engl J Med. 2017; 377:2053–62.
Article
72. Warren J, Sundaram K, Anis H, McLaughlin J, Patterson B, Higuera CA, et al. The association between weight-bearing status and early complications in hip fractures. Eur J Orthop Surg Traumatol. 2019; 29:1419–27.
Article
73. Ottesen TD, McLynn RP, Galivanche AR, Bagi PS, Zogg CK, Rubin LE, et al. Increased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients. Bone Joint J. 2018; 100B:1377–84.
74. Pfeufer D, Zeller A, Mehaffey S, Bocker W, Kammerlander C, Neuerburg C. Weight-bearing restrictions reduce postoperative mobility in elderly hip fracture patients. Arch Orthop Trauma Surg. 2019; 139:1253–9.
Article
75. Voeten SC, Nijmeijer WS, Vermeer M, Schipper IB, Hegeman JH; DHFA Taskforce study group. Validation of the Fracture Mobility Score against the Parker Mobility Score in hip fracture patients. Injury. 2020; 51:395–9.
Article
76. Ariza-Vega P, Jimenez-Moleon JJ, Kristensen MT. Non-weight-bearing status compromises the functional level up to 1 yr after hip fracture surgery. Am J Phys Med Rehabil. 2014; 93:641–8.
Article
77. Siebens HC, Sharkey P, Aronow HU, Horn SD, Munin MC, DeJong G, et al. Outcomes and weight-bearing status during rehabilitation after arthroplasty for hip fractures. PM R. 2012; 4:548–55.
Article
78. Sherrington C, Lord SR, Herbert RD. A randomized controlled trial of weight-bearing versus non-weight-bearing exercise for improving physical ability after usual care for hip fracture. Arch Phys Med Rehabil. 2004; 85:710–6.
79. Harkess JW, Crockarell JR. Arthroplasty of the hip. In : Azar FM, Beaty JH, Canale ST, editors. Campbell’s operative orthopaedics. 13th ed. Philadelphia, PA: Elsevier;2017. p. 2817–64.
80. Carlin L, Sibley K, Jenkinson R, Kontos P, McGlasson R, Kreder HJ, et al. Exploring Canadian surgeons’ decisions about postoperative weight bearing for their hip fracture patients. J Eval Clin Pract. 2018; 24:42–7.
Article
81. Robbins AS, Rubenstein LZ, Josephson KR, Schulman BL, Osterweil D, Fine G. Predictors of falls among elderly people: results of two populationbased studies. Arch Intern Med. 1989; 149:1628–33.
Article
82. Lee SY, Jung SH, Lee SU, Ha YC, Lim JY. Effect of balance training after hip fracture surgery: a systematic review and meta-analysis of randomized controlled studies. J Gerontol A Biol Sci Med Sci. 2019; 74:1679–85.
Article
83. Wu JQ, Mao LB, Wu J. Efficacy of balance training for hip fracture patients: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2019; 14:83.
Article
84. Martin-Martin LM, Valenza-Demet G, JimenezMoleon JJ, Cabrera-Martos I, Revelles-Moyano FJ, Valenza MC. Effect of occupational therapy on functional and emotional outcomes after hip fracture treatment: a randomized controlled trial. Clin Rehabil. 2014; 28:541–51.
Article
85. Uruma M, Momosaki R, Chono M, Fukumoto M, Watanabe T, Nakamura M, et al. Effectiveness of acute in-hospital occupational therapy for older patients with hip fracture. Geriatr Gerontol Int. 2019; 19:611–5.
Article
86. Lee SY, Jung SH, Lee SU, Ha YC, Lim JY. Is occupational therapy after hip fracture surgery effective in improving function? A systematic review and meta-analysis of randomized controlled studies. Am J Phys Med Rehabil. 2019; 98:292–8.
87. Heinrich S, Rapp K, Rissmann U, Becker C, Konig HH. Cost of falls in old age: a systematic review. Osteoporos Int. 2010; 21:891–902.
Article
88. Prestmo A, Hagen G, Sletvold O, Helbostad JL, Thingstad P, Taraldsen K, et al. Comprehensive geriatric care for patients with hip fractures: a prospective, randomised, controlled trial. Lancet. 2015; 385:1623–33.
Article
89. Milte R, Miller MD, Crotty M, Mackintosh S, Thomas S, Cameron ID, et al. Cost-effectiveness of individualized nutrition and exercise therapy for rehabilitation following hip fracture. J Rehabil Med. 2016; 48:378–85.
Article
90. Lahtinen A, Leppilahti J, Vahanikkila H, Harmainen S, Koistinen P, Rissanen P, et al. Costs after hip fracture in independently living patients: a randomised comparison of three rehabilitation modalities. Clin Rehabil. 2017; 31:672–85.
Article
91. Dyer SM, Crotty M, Fairhall N, Magaziner J, Beaupre LA, Cameron ID, et al. A critical review of the longterm disability outcomes following hip fracture. BMC Geriatr. 2016; 16:158.
Article
92. Mathew RO, Hsu WH, Young Y. Effect of comorbidity on functional recovery after hip fracture in the elderly. Am J Phys Med Rehabil. 2013; 92:686–96.
Article
93. Stott DJ, Handoll HH. Rehabilitation of older people after hip (proximal femoral) fracture. Cochrane Database Syst Rev. 2011; (8):ED000023.
Article
94. Mak J, Wong E, Cameron I; Australian and New Zealand Society for Geriatric Medicine. Australian and New Zealand Society for Geriatric Medicine: Position statement - orthogeriatric care. Australas J Ageing. 2011; 30:162–9.
95. Donohue K, Hoevenaars R, McEachern J, Zeman E, Mehta S. Home-based multidisciplinary rehabilitation following hip fracture surgery: what is the evidence? Rehabil Res Pract. 2013; 2013:875968.
Article
96. Mehta SP, Roy JS. Systematic review of home physiotherapy after hip fracture surgery. J Rehabil Med. 2011; 43:477–80.
Article
97. Turunen K, Salpakoski A, Edgren J, Tormakangas T, Arkela M, Kallinen M, et al. Physical activity after a hip fracture: effect of a multicomponent home-based rehabilitation program: a secondary analysis of a randomized controlled trial. Arch Phys Med Rehabil. 2017; 98:981–8.
98. Tseng MY, Liang J, Shyu YI, Wu CC, Cheng HS, Chen CY, et al. Effects of interventions on trajectories of health-related quality of life among older patients with hip fracture: a prospective randomized controlled trial. BMC Musculoskelet Disord. 2016; 17:114.
Article
99. Karlsson A, Berggren M, Gustafson Y, Olofsson B, Lindelof N, Stenvall M. Effects of geriatric interdisciplinary home rehabilitation on walking ability and length of hospital stay after hip fracture: a randomized controlled trial. J Am Med Dir Assoc. 2016; 17:464.e9–464.e15.
100. Salpakoski A, Tormakangas T, Edgren J, Kallinen M, Sihvonen SE, Pesola M, et al. Effects of a multicomponent home-based physical rehabilitation program on mobility recovery after hip fracture: a randomized controlled trial. J Am Med Dir Assoc. 2014; 15:361–8.
Article
101. Orwig DL, Hochberg M, Yu-Yahiro J, Resnick B, Hawkes WG, Shardell M, et al. Delivery and outcomes of a yearlong home exercise program after hip fracture: a randomized controlled trial. Arch Intern Med. 2011; 171:323–31.
Article
102. Tinetti ME, Baker DI, Gottschalk M, Williams CS, Pollack D, Garrett P, et al. Home-based multicomponent rehabilitation program for older persons after hip fracture: a randomized trial. Arch Phys Med Rehabil. 1999; 80:916–22.
Article
103. Magaziner J, Hawkes W, Hebel JR, Zimmerman SI, Fox KM, Dolan M, et al. Recovery from hip fracture in eight areas of function. J Gerontol A Biol Sci Med Sci. 2000; 55:M498–507.
Article
104. Fransen M, Woodward M, Norton R, Robinson E, Butler M, Campbell AJ. Excess mortality or institutionalization after hip fracture: men are at greater risk than women. J Am Geriatr Soc. 2002; 50:685–90.
Article
105. Latham NK, Harris BA, Bean JF, Heeren T, Goodyear C, Zawacki S, et al. Effect of a home-based exercise program on functional recovery following rehabilitation after hip fracture: a randomized clinical trial. JAMA. 2014; 311:700–8.
106. Mangione KK, Craik RL, Palombaro KM, Tomlinson SS, Hofmann MT. Home-based leg-strengthening exercise improves function 1 year after hip fracture: a randomized controlled study. J Am Geriatr Soc. 2010; 58:1911–7.
Article
107. Sherrington C, Lord SR. Home exercise to improve strength and walking velocity after hip fracture: a randomized controlled trial. Arch Phys Med Rehabil. 1997; 78:208–12.
Article
108. Scurrah A, Shiner CT, Stevens JA, Faux SG. Regional nerve blockade for early analgesic management of elderly patients with hip fracture: a narrative review. Anaesthesia. 2018; 73:769–83.
109. Munter KH, Clemmesen CG, Foss NB, Palm H, Kristensen MT. Fatigue and pain limit independent mobility and physiotherapy after hip fracture surgery. Disabil Rehabil. 2018; 40:1808–16.
110. Abou-Setta AM, Beaupre LA, Rashiq S, Dryden DM, Hamm MP, Sadowski CA, et al. Comparative effectiveness of pain management interventions for hip fracture: a systematic review. Ann Intern Med. 2011; 155:234–45.
Article
111. Guay J, Parker MJ, Griffiths R, Kopp SL. Peripheral nerve blocks for hip fractures: a Cochrane review. Anesth Analg. 2018; 126:1695–704.
112. Guay J, Parker MJ, Griffiths R, Kopp S. Peripheral nerve blocks for hip fractures. Cochrane Database Syst Rev. 2017; 5:CD001159.
Article
113. Rowlands M, Walt GV, Bradley J, Mannings A, Armstrong S, Bedforth N, et al. Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomised controlled trial. BMJ Open. 2018; 8:e019650.
Article
114. Morrison RS, Dickman E, Hwang U, Akhtar S, Ferguson T, Huang J, et al. Regional nerve blocks improve pain and functional outcomes in hip fracture: a randomized controlled trial. J Am Geriatr Soc. 2016; 64:2433–9.
Article
115. Nie H, Zhao B, Zhang YQ, Jiang YH, Yang YX. Pain and cognitive dysfunction are the risk factors of delirium in elderly hip fracture Chinese patients. Arch Gerontol Geriatr. 2012; 54:e172–4.
Article
116. Mouzopoulos G, Vasiliadis G, Lasanianos N, Nikolaras G, Morakis E, Kaminaris M. Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. J Orthop Traumatol. 2009; 10:127–33.
Article
117. Haslam L, Lansdown A, Lee J, van der Vyver M. Survey of current practices: peripheral nerve block utilization by ED physicians for treatment of pain in the hip fracture patient population. Can Geriatr J. 2013; 16:16–21.
Article
118. Abrahams MS, Aziz MF, Fu RF, Horn JL. Ultrasound guidance compared with electrical neurostimulation for peripheral nerve block: a systematic review and meta-analysis of randomized controlled trials. Br J Anaesth. 2009; 102:408–17.
Article
119. Korbe S, Udoji EN, Ness TJ, Udoji MA. Ultrasound-guided interventional procedures for chronic pain management. Pain Manag. 2015; 5:465–82.
Article
120. Shim JH. Is ultrasound-guided procedure entirely reliable? Korean J Anesthesiol. 2017; 70:487–8.
Article
121. Balk E, Ellis AG, Di M, Adam GP, Trikalinos TA. Venous thromboembolism prophylaxis in major orthopedic surgery: systematic review update. Rockville, MD: Agency for Healthcare Research and Quality;2017.
122. Leizorovicz A, Turpie AG, Cohen AT, Wong L, Yoo MC, Dans A, et al. Epidemiology of venous thromboembolism in Asian patients undergoing major orthopedic surgery without thromboprophylaxis. The SMART study. J Thromb Haemost. 2005; 3:28–34.
Article
123. Yhim HY, Jang MJ, Bang SM, Kim KH, Kim YK, Nam SH, et al. Incidence of venous thromboembolism following major surgery in Korea: from the Health Insurance Review and Assessment Service database. J Thromb Haemost. 2014; 12:1035–43.
Article
124. Jang MJ, Bang SM, Oh D. Incidence of venous thromboembolism in Korea: from the Health Insurance Review and Assessment Service database. J Thromb Haemost. 2011; 9:85–91.
Article
125. Heit JA, O’Fallon WM, Petterson TM, Lohse CM, Silverstein MD, Mohr DN, et al. Relative impact of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med. 2002; 162:1245–8.
126. Kuperman EF, Schweizer M, Joy P, Gu X, Fang MM. The effects of advanced age on primary total knee arthroplasty: a meta-analysis and systematic review. BMC Geriatr. 2016; 16:41.
Article
127. Chang JD, Yoo JH, Lee SS, Kim TY, Jung KH, Kim YK. Bipolar hemiarthroplasty for hip fractures in patients aged over 90 years: the factors influencing the postoperative mortality. J Korean Hip Soc. 2010; 22:283–90.
128. Monticone M, Ambrosini E, Brunati R, Capone A, Pagliari G, Secci C, et al. How balance task-specific training contributes to improving physical function in older subjects undergoing rehabilitation following hip fracture: a randomized controlled trial. Clin Rehabil. 2018; 32:340–51.
Article
129. Tang Y, Wang K, Shi Z, Yang P, Dang X. A RCT study of rivaroxaban, low-molecular-weight heparin, and sequential medication regimens for the prevention of venous thrombosis after internal fixation of hip fracture. Biomed Pharmacother. 2017; 92:982–8.
Article
130. Wald HL, Ma A, Bratzler DW, Kramer AM. Indwelling urinary catheter use in the postoperative period: analysis of the national surgical infection prevention project data. Arch Surg. 2008; 143:551–7.
131. Kuy S, Gupta R, Roy C, Awad S. Incidence of catheterassociated urinary tract infections with compliance with preventive guidelines. JAMA Surg. 2020; 155:661–2.
Article
132. Halleberg Nyman M, Gustafsson M, Langius-Eklof A, Johansson JE, Norlin R, Hagberg L. Intermittent versus indwelling urinary catheterisation in hip surgery patients: a randomised controlled trial with cost-effectiveness analysis. Int J Nurs Stud. 2013; 50:1589–98.
133. Skelly JM, Guyatt GH, Kalbfleisch R, Singer J, Winter L. Management of urinary retention after surgical repair of hip fracture. CMAJ. 1992; 146:1185–9.
134. Michelson JD, Lotke PA, Steinberg ME. Urinarybladder management after total joint-replacement surgery. N Engl J Med. 1988; 319:321–6.
Article
135. Center JR, Bliuc D, Nguyen TV, Eisman JA. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007; 297:387–94.
Article
136. Colon-Emeric C, Kuchibhatla M, Pieper C, Hawkes W, Fredman L, Magaziner J, et al. The contribution of hip fracture to risk of subsequent fractures: data from two longitudinal studies. Osteoporos Int. 2003; 14:879–83.
137. Kanis JA, Johnell O, De Laet C, Johansson H, Oden A, Delmas P, et al. A meta-analysis of previous fracture and subsequent fracture risk. Bone. 2004; 35:375–82.
Article
138. Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA 3rd, Berger M. Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res. 2000; 15:721–39.
Article
139. Solomon DH, Finkelstein JS, Katz JN, Mogun H, Avorn J. Underuse of osteoporosis medications in elderly patients with fractures. Am J Med. 2003; 115:398–400.
Article
140. Bawa HS, Weick J, Dirschl DR. Anti-osteoporotic therapy after fragility fracture lowers rate of subsequent fracture: analysis of a large population sample. J Bone Joint Surg Am. 2015; 97:1555–62.
141. Soong YK, Tsai KS, Huang HY, Yang RS, Chen JF, Wu PC, et al. Risk of refracture associated with compliance and persistence with bisphosphonate therapy in Taiwan. Osteoporos Int. 2013; 24:511–21.
Article
142. Kim TY, Ha YC, Kang BJ, Lee YK, Koo KH. Does early administration of bisphosphonate affect fracture healing in patients with intertrochanteric fractures? J Bone Joint Surg Br. 2012; 94:956–60.
Article
143. Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, et al. Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med. 2007; 357:1799–809.
Article
144. Li Y, Zhao WB, Wang DL, He Q, Li Q, Pei FX, et al. Treatment of osteoporotic intertrochanteric fractures by zoledronic acid injection combined with proximal femoral nail anti-rotation. Chin J Traumatol. 2016; 19:259–63.
Article
145. Beaupre LA, Morrish DW, Hanley DA, Maksymowych WP, Bell NR, Juby AG, et al. Oral bisphosphonates are associated with reduced mortality after hip fracture. Osteoporos Int. 2011; 22:983–91.
Article
146. Cecilia D, Jodar E, Fernandez C, Resines C, Hawkins F. Effect of alendronate in elderly patients after low trauma hip fracture repair. Osteoporos Int. 2009; 20:903–10.
Article
147. Osaki M, Tatsuki K, Hashikawa T, Norimatsu T, Chiba K, Motokawa S, et al. Beneficial effect of risedronate for preventing recurrent hip fracture in the elderly Japanese women. Osteoporos Int. 2012; 23:695–703.
Article
148. Peng J, Liu Y, Chen L, Peng K, Xu Z, Zhang D, et al. Bisphosphonates can prevent recurrent hip fracture and reduce the mortality in osteoporotic patient with hip fracture: a meta-analysis. Pak J Med Sci. 2016; 32:499–504.
Article
149. Lee SY, Jung SH, Lee SU, Ha YC, Lim JY. Can bisphosphonates prevent recurrent fragility fractures? A systematic review and meta-analysis of randomized controlled trials. J Am Med Dir Assoc. 2018; 19:384–90.
Article
150. Kim C, Sung J, Lee JH, Kim WS, Lee GJ, Jee S, et al. Clinical practice guideline for cardiac rehabilitation in Korea. Ann Rehabil Med. 2019; 43:355–443.
Article
151. Invernizzi M, de Sire A, D’Andrea F, Carrera D, Reno F, Migliaccio S, et al. Effects of essential amino acid supplementation and rehabilitation on functioning in hip fracture patients: a pilot randomized controlled trial. Aging Clin Exp Res. 2019; 31:1517–24.
Article
152. Torres MJ, Feart C, Samieri C, Dorigny B, Luiking Y, Berr C, et al. Poor nutritional status is associated with a higher risk of falling and fracture in elderly people living at home in France: the Three-City cohort study. Osteoporos Int. 2015; 26:2157–64.
Article
153. Miyanishi K, Jingushi S, Torisu T. Mortality after hip fracture in Japan: the role of nutritional status. J Orthop Surg (Hong Kong). 2010; 18:265–70.
Article
154. Gumieiro DN, Rafacho BP, Goncalves AF, Tanni SE, Azevedo PS, Sakane DT, et al. Mini Nutritional Assessment predicts gait status and mortality 6 months after hip fracture. Br J Nutr. 2013; 109:1657–61.
Article
155. Malafarina V, Reginster JY, Cabrerizo S, Bruyere O, Kanis JA, Martinez JA, et al. Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture. Nutrients. 2018; 10:555.
Article
156. Paillaud E, Bories PN, Le Parco JC, Campillo B. Nutritional status and energy expenditure in elderly patients with recent hip fracture during a 2-month follow-up. Br J Nutr. 2000; 83:97–103.
Article
157. Hedstrom M. Hip fracture patients, a group of frail elderly people with low bone mineral density, muscle mass and IGF-I levels. Acta Physiol Scand. 1999; 167:347–50.
158. Mahran DG, Farouk O, Ismail MA, Alaa MM, Eisa A, Ragab II. Effectiveness of home based intervention program in reducing mortality of hip fracture patients: a non-randomized controlled trial. Arch Gerontol Geriatr. 2019; 81:8–17.
Article
159. Lonnie M, Hooker E, Brunstrom JM, Corfe BM, Green MA, Watson AW, et al. Protein for life: review of optimal protein intake, sustainable dietary sources and the effect on appetite in ageing adults. Nutrients. 2018; 10:360.
Article
160. Campbell WW, Trappe TA, Jozsi AC, Kruskall LJ, Wolfe RR, Evans WJ. Dietary protein adequacy and lower body versus whole body resistive training in older humans. J Physiol. 2002; 542(Pt 2):631–42.
161. World Health Organization. Protein and amino acid requirements in human nutrition. Geneva, Swizerland: World Health Organization;2002.
162. Deutz NE, Bauer JM, Barazzoni R, Biolo G, Boirie Y, Bosy-Westphal A, et al. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group. Clin Nutr. 2014; 33:929–36.
Article
163. Avenell A, Smith TO, Curtain JP, Mak JC, Myint PK. Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database Syst Rev. 2016; 11:CD001880.
Article
164. Espaulella J, Guyer H, Diaz-Escriu F, Mellado-Navas JA, Castells M, Pladevall M. Nutritional supplementation of elderly hip fracture patients: a randomized, double-blind, placebo-controlled trial. Age Ageing. 2000; 29:425–31.
Article
165. Tkatch L, Rapin CH, Rizzoli R, Slosman D, Nydegger V, Vasey H, et al. Benefits of oral protein supplementation in elderly patients with fracture of the proximal femur. J Am Coll Nutr. 1992; 11:519–25.
Article
166. Aquilani R, Zuccarelli Ginetto C, Rutili C, Pisano P, Pasini E, Baldissarro E, et al. Supplemented amino acids may enhance the walking recovery of elderly subjects after hip fracture surgery. Aging Clin Exp Res. 2019; 31:157–60.
Article
167. Wyers CE, Reijven PL, Breedveld-Peters JJ, Denissen KF, Schotanus MG, van Dongen MC, et al. Efficacy of nutritional intervention in elderly after hip fracture: a multicenter randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2018; 73:1429–37.
Article
168. Niitsu M, Ichinose D, Hirooka T, Mitsutomi K, Morimoto Y, Sarukawa J, et al. Effects of combination of whey protein intake and rehabilitation on muscle strength and daily movements in patients with hip fracture in the early postoperative period. Clin Nutr. 2016; 35:943–9.
Article
169. Ekinci O, Yanik S, Terzioglu Bebitoglu B, Yilmaz Akyuz E, Dokuyucu A, Erdem S. Effect of Calcium β-Hydroxy-β-Methylbutyrate (CaHMB), vitamin D, and protein supplementation on postoperative immobilization in malnourished older adult patients with hip fracture: a randomized controlled study. Nutr Clin Pract. 2016; 31:829–35.
170. Beaupre LA, Jones CA, Saunders LD, Johnston DW, Buckingham J, Majumdar SR. Best practices for elderly hip fracture patients: a systematic overview of the evidence. J Gen Intern Med. 2005; 20:1019–25.
Article
171. Swift C, Ftouh S, Langford P, Chesser TS, Johanssen A. Interdisciplinary management of hip fracture. Clin Med (Lond). 2016; 16:541–4.
Article
172. Yoo JI, Ha YC, Lim JY, Kang H, Yoon BH, Kim H. Early rehabilitation in elderly after arthroplasty versus internal fixation for unstable intertrochanteric fractures of femur: systematic review and meta-analysis. J Korean Med Sci. 2017; 32:858–67.
Article
173. Smith TO, Collier T, Sheehan KJ, Sherrington C. The uptake of the hip fracture core outcome set: analysis of 20 years of hip fracture trials. Age Ageing. 2019; 48:595–8.
Article
174. Haywood KL, Griffin XL, Achten J, Costa ML. Developing a core outcome set for hip fracture trials. Bone Joint J. 2014; 96-B:1016–23.
Article
175. Armstrong MJ, Mullins CD, Gronseth GS, Gagliardi AR. Impact of patient involvement on clinical practice guideline development: a parallel group study. Implement Sci. 2018; 13:55.
Article
176. National Clinical Guideline Centre. The management of hip fracture in adults [Internet]. London, UK: National Clinical Guideline Centre;2011. [cited 2021 May 24]. Available from: https://www.nice.org.uk/guidance/cg124/evidence/full-guideline-pdf-183081997.
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