J Wound Manag Res.  2021 Jun;17(2):85-93. 10.22467/jwmr.2020.01277.

Degrees of Arterial Stenosis and Other Factors Related with Diabetic Foot Wound Severity

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Konkuk University Chungju Hospital, Konkuk University School of Medicine, Chungju, Korea

Abstract

Background
Few studies have addressed which blood vessels are affected by arterial stenosis in patients with diabetic foot (DF) and the severity thereof. Furthermore, whether the severity of arterial stenosis is significantly correlated to DF severity was yet to be established. We analyzed the association between the severity of arterial stenosis and DF wound severity, along with a variety of relevant factors.
Methods
Seventy-one cases hospitalized with DF were evaluated. To assess the degree of arterial stenosis of the five major arteries of the lower extremity (femoral, popliteal, anterior tibial, posterior tibial and peroneal artery), we performed computed tomography angiography, and quantified arterial stenosis using Bollinger scores. We then assessed DF severity and calculated self-reported wound scores. We also analyzed factors that can affect DF severity and the degree of arterial stenosis in the lower extremities.
Results
There was no significant association between the mean total Bollinger score and wound severity. Albumin, protein, and Bollinger scores of femoral arteries showed significant association with wound severity, and age and ankle-brachial index (ABI) showed significant association with mean total Bollinger scores (P<0.05). Albumin and Bollinger scores of femoral arteries had significant association with wound severity, and age and ABI showed significant association with mean total Bollinger scores (P<0.05).
Conclusion
There was no significant association between the degree of vascular obstruction and the severity of DF. Our results indicate that surgeons should consider the other factors above to ensure appropriate management of patients with DF and assess the prognosis.

Keyword

Diabetes mellitus; Diabetic foot; Peripheral arterial disease; Arterial occlusive diseases; Computed tomography angiography
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