Korean J Head Neck Oncol.  2020 Nov;36(2):55-59. 10.21593/kjhno/2020.36.2.55.

A Case of Hemophagocytic Lymphohistiocytosis Presenting with Neck Mass in a Child

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu, Daegu, Korea

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening one syndrome of excessive immune activation. This immune dysregulation disorder is prominently associated with cytopenias and combinations of clinical signs and extreme inflammation symptoms. For survival, it is important to diagnose early and treat appropriately. We report a case of 10 years old boy who was admitted to the hospital with a month history of fever and cervical lymph node enlargement. There were signs of hemophagocytic histiocytosis in the lymph node and bone marrow. The etiology, diagnosis, and treatment of hemophagocytic lymphohistiocytosis are reviewed.

Keyword

Hemophagocytic lymphohistiocytosis; Head and neck neoplasm; Fever; Child; Differential diagnosis
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