Korean J Transplant.  2020 Dec;34(Supple 1):S164. 10.4285/ATW2020.PO-1243.

The impact of model for end-stage liver disease (MELD) score on liver transplant outcomes in low volume liver transplantation center: single center experience

• Pyo SH
• Kim D
• Lee D
• Choi ST
• Park YH

• KMID: 2509354
• DOI: http://doi.org/10.4285/ATW2020.PO-1243

Abstract

Background
In June of 2016, the model for end-stage liver disease (MELD) score was employed in Korea instead of the ChildTurcotte-Pugh (CTP) score. This study compared the outcomes of deceased donor liver transplantation (DDLT) before and after MELD system.
Methods
From January 2014 to December 2018, 48 patients were underwent DDLT in a single center. Patients were divided into two groups according in a same time period (2.5 years) from MELD allocation time (2016 June). Laboratory data and clinical outcomes were collected and analyzed retrospectively.
Results
There were 22 in the pre-MELD group and 26 in the MELD group. There was no difference in age, sex, ABO type, etiology for liver transplantation, CTP score, operation time, cold ischemic time, and amount of red blood cell transfusion. However, the MELD score of the two groups differed significantly (36.2±4.9 in the MELD group, 27.7±11.8 in the pre-MELD group, P<0.001). MELD group revealed longer intensive care unit stay and hospital stay than pre-MELD group (11.2±9.5 vs. 5.7±4.5, P=0.018; 36.8±26 vs. 22.8±9.3, P=0.016). Mean follow-up time was 32.8 months and 1-year survival rate was lower in MELD group (61.5% vs. 86.4%) although statistically insignificant (P=0.056).
Conclusions
After MELD allocation, high MELD patients increased in DDLT and consequently needed had longer recovery time. Also they might have negative results in survivals. According to a small volume center’s experience, these problems were related with severe organ shortage in Korea rather than MELD.