Korean J Vet Res.  2020 Sep;60(3):173-177. 10.14405/kjvr.2020.60.3.173.

Genotypic characterization of fluoroquinolone-resistant Escherichia coli isolates from edible offal

Affiliations
  • 1College of Veterinary Medicine & Zoonoses Research Institute, Kyungpook National University, Daegu 41566, Korea

Abstract

Abstract: Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics of FQ-resistant E. coli from edible offal. A total of 22 FQ-resistant E. coli isolates were tested. A double mutation in each gyrA and parC led the highest MIC. Four (18.2%) isolates carried plasmid-mediated quinolone resistance genes. The fimH, eaeA, escV, astA, and iucC genes were confirmed. Seventeen isolates (77.3%) were positive for plasmid replicons. The isolates showed high genetic heterogeneity based on pulsed-field gel electrophoresis patterns.

Keyword

Escherichia coli; edible offal; fluoroquinolones; quinolone resistance-determining region; molecular typing
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