Korean J Thorac Cardiovasc Surg.  2020 Aug;53(4):217-221. 10.5090/kjtcs.2020.53.4.217.

Reflux Following Esophagectomy for Esophageal Cancer

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

Gastroesophageal reflux is a common problem after gastroesophageal resection and reconstruction,despite the routine prescription of proton pump inhibitors (PPIs). Resectionof the lower esophageal sphincter and excision of the vagus nerve are generally thoughtto be the main factors that interfere with gastric motor function. However, physiologicalstudies of reflux symptoms after esophagectomy are still lacking. Gastroesophageal refluxoccurs frequently after esophagectomy, but there is no known effective method to preventit. Therefore, in order to manage gastroesophageal reflux after esophagectomy, strictlifestyle modifications and gastric acid suppression treatment such as PPIs are needed, andfurther clinical studies are required.

Keyword

Esophageal neoplasms; Gastroesophageal reflux; Esophagectomy
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