Clin Endosc.  2020 Jul;53(4):410-416. 10.5946/ce.2020.161.

Roles of Capsule Endoscopy and Device-Assisted Enteroscopy in the Diagnosis and Treatment of Small-Bowel Tumors

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

With the development of capsule endoscopy (CE) and device-assisted enteroscopy (DAE), the incidence of small-bowel tumors has increased and the characteristics of these tumors have changed. In addition, the diagnostic and therapeutic approaches for small-bowel tumors have diversified. CE is a simple, noninvasive method that aid in the visualization the entire small bowel. CE is considered the initial approach for small-bowel tumors. DAE can be used to perform endoscopic procedures such as bleeding control, polypectomy, stent insertion, and tattooing, as well as for diagnosis through visualization or tissue sampling. Therapeutic intervention with DAE is particularly useful in polyposis syndromes such as familial adenomatous polyposis and Peutz-Jeghers syndrome. This review will discuss the roles of CE and DAE in the diagnosis and treatment of small-bowel tumors.

Keyword

Capsule endoscopy; Device-assisted enteroscopy; Familial adenomatous polyposis; Peutz-Jeghers syndrome; Smallbowel tumors

Figure

  • Fig. 1. Surveillance and polypectomy using capsule endoscopy and device-assisted enteroscopy in a patient with Peutz-Jeghers syndrome. (A, B) Surveillance capsule endoscopy images showing several polyps >10 mm in the jejunum. (C-E) Enteroscopic polypectomy using device-assisted enteroscopy.


Reference

1. Islam RS, Leighton JA, Pasha SF. Evaluation and management of small-bowel tumors in the era of deep enteroscopy. Gastrointest Endosc. 2014; 79:732–740.
Article
2. Cheung DY, Kim JS, Shim KN, Choi MG. The usefulness of capsule endoscopy for small bowel tumors. Clin Endosc. 2016; 49:21–25.
Article
3. Chen WG, Shan GD, Zhang H, et al. Double-balloon enteroscopy in small bowel tumors: a Chinese single-center study. World J Gastroenterol. 2013; 19:3665–3671.
Article
4. Volk N, Lacy B. Anatomy and physiology of the small bowel. Gastrointest Endosc Clin N Am. 2017; 27:1–13.
Article
5. Sulbaran M, de Moura E, Bernardo W, et al. Overtube-assisted enteroscopy and capsule endoscopy for the diagnosis of small-bowel polyps and tumors: a systematic review and meta-analysis. Endosc Int Open. 2016; 4:E151–E163.
Article
6. Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS. Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg. 2009; 249:63–71.
7. Kim JH, Moon W. Optimal diagnostic approaches for patients with suspected small bowel disease. Clin Endosc. 2016; 49:364–369.
Article
8. Paski SC, Semrad CE. Small bowel tumors. Gastrointest Endosc Clin N Am. 2009; 19:461–479.
Article
9. Hatzaras I, Palesty JA, Abir F, et al. Small-bowel tumors: epidemiologic and clinical characteristics of 1260 cases from the connecticut tumor registry. Arch Surg. 2007; 142:229–235.
10. Aparicio T, Zaanan A, Svrcek M, et al. Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment. Dig Liver Dis. 2014; 46:97–104.
Article
11. Bouvier AM, Robaszkiewicz M, Jooste V, et al. Trends in incidence of small bowel cancer according to histology: a population-based study. J Gastroenterol. 2020; 55:181–188.
Article
12. Pourmand K, Itzkowitz SH. Small bowel neoplasms and polyps. Curr Gastroenterol Rep. 2016; 18:23.
Article
13. Barsouk A, Rawla P, Barsouk A, Thandra KC. Epidemiology of cancers of the small Iintestine: trends, risk factors, and prevention. Med Sci (Basel). 2019; 7:46.
14. Puccini A, Battaglin F, Lenz HJ. Management of advanced small bowel cancer. Curr Treat Options Oncol. 2018; 19:69.
Article
15. Sakae H, Kanzaki H, Nasu J, et al. The characteristics and outcomes of small bowel adenocarcinoma: a multicentre retrospective observational study. Br J Cancer. 2017; 117:1607–1613.
Article
16. Gerson LB. Capsule endoscopy and deep enteroscopy: indications for the practicing clinician. Gastroenterology. 2009; 137:1197–1201.
Article
17. Baichi MM, Arifuddin RM, Mantry PS. Small-bowel masses found and missed on capsule endoscopy for obscure bleeding. Scand J Gastroenterol. 2007; 42:1127–1132.
Article
18. Cheung DY, Lee IS, Chang DK, et al. Capsule endoscopy in small bowel tumors: a multicenter Korean study. J Gastroenterol Hepatol. 2010; 25:1079–1086.
Article
19. Rondonotti E, Pennazio M, Toth E, et al. Small-bowel neoplasms in patients undergoing video capsule endoscopy: a multicenter European study. Endoscopy. 2008; 40:488–495.
Article
20. Bailey AA, Debinski HS, Appleyard MN, et al. Diagnosis and outcome of small bowel tumors found by capsule endoscopy: a three-center Australian experience. Am J Gastroenterol. 2006; 101:2237–2243.
Article
21. Apostolopoulos P, Liatsos C, Gralnek IM, et al. Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding. Gastrointest Endosc. 2007; 66:1174–1181.
Article
22. Enns RA, Hookey L, Armstrong D, et al. Clinical practice guidelines for the use of video capsule endoscopy. Gastroenterology. 2017; 152:497–514.
23. Iaquinto G, Fornasarig M, Quaia M, et al. Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis. Gastrointest Endosc. 2008; 67:61–67.
Article
24. Schulmann K, Hollerbach S, Kraus K, et al. Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes. Am J Gastroenterol. 2005; 100:27–37.
Article
25. Burke CA, Santisi J, Church J, Levinthal G. The utility of capsule endoscopy small bowel surveillance in patients with polyposis. Am J Gastroenterol. 2005; 100:1498–1502.
Article
26. Ohmiya N, Nakamura M, Takenaka H, et al. Management of small-bowel polyps in Peutz-Jeghers syndrome by using enteroclysis, double-balloon enteroscopy, and videocapsule endoscopy. Gastrointest Endosc. 2010; 72:1209–1216.
Article
27. Gupta A, Postgate AJ, Burling D, et al. A prospective study of MR enterography versus capsule endoscopy for the surveillance of adult patients with Peutz-Jeghers syndrome. AJR Am J Roentgenol. 2010; 195:108–116.
Article
28. Lewis BS, Eisen GM, Friedman S. A pooled analysis to evaluate results of capsule endoscopy trials. Endoscopy. 2005; 37:960–965.
Article
29. Ormeci AC, Akyuz F, Baran B, et al. Retention during capsule endoscopy: is it a real problem in routine practice? J Int Med Res. 2016; 44:968–975.
Article
30. Purdy M, Heikkinen M, Juvonen P, Voutilainen M, Eskelinen M. Characteristics of patients with a retained wireless capsule endoscope (WCE) necessitating laparotomy for removal of the capsule. In Vivo. 2011; 25:707–710.
31. Tang L, Huang LY, Cui J, Wu CR. Effect of double-balloon enteroscopy on diagnosis and treatment of small-bowel diseases. Chin Med J (Engl). 2018; 131:1321–1326.
Article
32. Mitsui K, Tanaka S, Yamamoto H, et al. Role of double-balloon endoscopy in the diagnosis of small-bowel tumors: the first Japanese multicenter study. Gastrointest Endosc. 2009; 70:498–504.
Article
33. Zhang C, Hong L, Zhang T, et al. Clinical characteristics of small bowel tumors diagnosed by double-balloon endoscopy: experience from a Chinese tertiary hospital. Turk J Gastroenterol. 2020; 31:30–35.
34. Zhang Q, He Q, Liu J, Ma F, Zhi F, Bai Y. Combined use of capsule endoscopy and double-balloon enteroscopy in the diagnosis of obscure gastrointestinal bleeding: meta-analysis and pooled analysis. Hepatogastroenterology. 2013; 60:1885–1891.
35. Ross A, Mehdizadeh S, Tokar J, et al. Double balloon enteroscopy detects small bowel mass lesions missed by capsule endoscopy. Dig Dis Sci. 2008; 53:2140–2143.
Article
36. Ohmiya N, Nakamura M, Tahara T, et al. Management of small-bowel polyps at double-balloon enteroscopy. Ann Transl Med. 2014; 2:30.
37. Saygili F, Saygili SM, Oztas E. Examining the whole bowel, double balloon enteroscopy: indications, diagnostic yield and complications. World J Gastrointest Endosc. 2015; 7:247–252.
Article
38. Tsuboi A, Kuwai T, Nishimura T, et al. Safety and efficacy of self-expandable metallic stents in malignant small bowel obstructions. World J Gastroenterol. 2016; 22:9022–9027.
Article
39. Lee H, Park JC, Shin SK, Lee SK, Lee YC. Preliminary study of enteroscopy-guided, self-expandable metal stent placement for malignant small bowel obstruction. J Gastroenterol Hepatol. 2012; 27:1181–1186.
Article
40. Römmele C, Ebigbo A, Schrempf M, Messmann H, Gölder SK. Detection rate and clinical relevance of ink tattooing during balloon-assisted enteroscopy. Gastroenterol Res Pract. 2017; 2017:4969814.
Article
Full Text Links
  • CE
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr