Clin Endosc.  2020 Jul;53(4):402-409. 10.5946/ce.2020.143.

Roles of Capsule Endoscopy and Balloon-Assisted Enteroscopy in the Optimal Management of Small Bowel Bleeding

  • 1Department of Gastroenterology, Beni-Suef University, Qism Bani Sweif, Egypt
  • 2Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan
  • 3Shinozaki Medical Clinic, Utsunomiya, Japan
  • 4Department of Surgery, Jichi Medical University, Shimotsuke, Japan


The small bowel had long been considered a dark unapproachable tunnel until the invention of capsule endoscopy and doubleballoon enteroscopy in the 21st century, which revolutionized the diagnosis and management of small bowel diseases, including bleeding. Various imaging modalities such as computed tomographic enterography, angiography, capsule endoscopy, and balloonassisted enteroscopy play vital roles in the diagnosis and management of small bowel bleeding. The choice of modality to use and timing of application differ according to the availability of the modalities, patient’s history, and physician’s experience. Small bowel bleeding is managed using different strategies as exemplified by medical treatment, interventional radiology, endoscopic therapy, or surgical intervention. Balloon-assisted enteroscopy enables endoscopic interventions to control small bowel bleeding, including electrocautery, argon plasma coagulation, clip application, and tattooing as a prelude to surgery. In this article, we clarify the recent approaches to the optimal diagnosis and management of patients with small bowel bleeding.


Balloon-assisted enteroscopy; Capsule endoscopy; Double-balloon enteroscopy; Small bowel bleeding
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