J Korean Med Assoc.  2020 Jul;63(7):374-381. 10.5124/jkma.2020.63.7.374.

Diagnosis and management of Kawasaki disease

Affiliations
  • 1Division of Pediatric Cardiology, Department of Pediatrics, Kyungpook National University Children’s Hospital, School of Medicine, Kyungpook National University, Daegu, Korea

Abstract

Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a common form of vasculitis in childhood. Among the recent trends in Kawasaki disease, it is notable that the prevalence rate is increasing, and the proportion of “incomplete” Kawasaki disease is also increasing. A delayed diagnosis with prolonged fever can cause complications, such as coronary artery aneurysm and decreased myocardial contractility. These complications might lead to significant morbidity and mortality. Kawasaki disease is diagnosed when the patient meets the principal criteria for clinical symptoms. Following the diagnostic criteria can prevent overdiagnosis but lead to missing of the incomplete form of the disease. Therefore, it is important to accurately understand Kawasaki disease. As the coronavirus disease 2019 (COVID-19) pandemic continues, concerns about a novel severe Kawasaki-like disease in children related to COVID-19 emerges. Indeed, there have been several reports of Kawasaki-like disease related to COVID-19 in children. Kawasaki disease is no longer rare and is often encountered at hospitals. This paper will provide useful and accurate information on Kawasaki disease.

Keyword

Mucocutaneous lymph node syndrome; Lymphadenopathy; Aspirin; Calmette-Guerin Bacillus vaccine; Intravenous immunoglobulins; 점막 피부 림프절 증후군; 림프절병증; 아스피린; BCG 백신; 정맥 내 면역글로불린
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