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High-on-Aspirin Platelet Reactivity Differs Between Recurrent Ischemic Stroke Associated With Extracranial and Intracranial Atherosclerosis

Noh KC, Choi Hy, Woo HG, Chang JY, Heo SH, Chang Di, Kim BJ

Background and Purpose Ischemic stroke recurs despite the use of antiplatelet agents. Various mechanisms are involved in recurrence due to intracranial atherosclerosis (ICAS) and extracranial atherosclerosis (ECAS). High-on-aspirin platelet reactivity...
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Statin and aspirin for chemoprevention of hepatocellular carcinoma: Time to use or wait further?

Goh MJ, Sinn DH

Preclinical studies highlighted potential therapeutic applications of aspirin and statins as anticancer agents based on their pleiotropic effects. Epidemiologic studies suggested the role of aspirin and statins in the chemoprevention...
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Comparative Study of Ex Vivo Antiplatelet Activity of Aspirin and Cilostazol in Patients with Diabetes and High Risk of Cardiovascular Disease

Hong S, Lee WJ, Park CY

Background: The role of aspirin in primary cardiovascular disease prevention in patients with diabetes remains controversial. However, some studies have suggested beneficial effects of cilostazol on cardiovascular disease in patients...
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Safety and efficacy of low-dose aspirin in patients with coronary artery spasm: long-term clinical follow-up

Choi BG, Kim KH, Rha SW

Background: Aspirin is known to aggravate coronary artery spasm (CAS) regardless of the dose (100–325 mg/day). However, it is unclear whether low-dose aspirin (LDA; 100 mg) has deleterious impacts on...
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Treatment of In-Stent Stenosis Following Flow Diversion of Intracranial Aneurysms with Cilostazol and Clopidogrel

Dowlati E, Pasko KBD, Liu J, Miller CA, Felbaum DR, Sur S, Chang JJ, Liu AH, Armonda RA, Mai JC

In-stent stenosis is a feared complication of flow diversion treatment for cerebral aneurysms. We present 2 cases of patients treated with pipeline flow diversion for unruptured cerebral aneurysms. Initial perioperative...
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Clinical Practice Patterns of Hypertensive Disease in Pregnancy among Korean Obstetricians

Ahn TG, Kim YH, Kim YS, Shin JE, Oh YL, Lee SA, Lee M, Lee GSR, Kim SY, Kim SM, Hwang JY

Purpose: The purpose of this study was to investigate the clinical practice patterns of Korean obstetricians and gynecologists the diagnosis and management of hypertensive disease in pregnant women. Methods: From...
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Impact of Intravenous Aspirin Administration on Ventriculostomy-Associated Hemorrhage in Coiled Acute Subarachnoid Hemorrhage Patients

Evans D, Flood R, Davies O, Wareham J, Mortimer A

Purpose: Aspirin has beneficial effects on coiling, even in acute subarachnoid hemorrhage, but there is also a perceived risk of increased bleeding and, importantly, a concern regarding ventriculostomy-associated hemorrhage (VAH)...
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Incidence and Mortality Associated with Cardiovascular Medication among Hypertensive COVID-19 Patients in South Korea

Oh TK, Cho HW, Suh JW, Song IA

Purpose: We aimed to investigate whether the use of cardiovascular drugs in coronavirus disease 2019 (COVID-19) patients with hypertension as a comorbidity has a significant effect on the incidence and...
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Relationship Between Cerebral Microbleeds and Aspirin Use Regarding White Matter Hyperintensity Volume

Kim CK, Han JH, Jeong HY, Oh K, Park JH, Kwon HM

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Dexamethasone reduces infectious bursal disease mortality in chickens

Shin SY, Han TH, Kwon HJ, Kim SJ, Ryu PD

Very virulent infectious bursal disease virus (vvIBDV) causes high mortality in chickens but measures to reduce the mortality have not been explored. Chickens (8–9 weeks) were treated with 3 agents...
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Endoscopic Ultrasound-guided Fine-needle Aspiration Biopsy of a Renal Mass

Ha J, Kim D, Kim H, Park CK, Jung J, Chung YJ, Lee J, Ryu H

Traditionally, tissue biopsies of kidney lesions are usually performed with CT or percutaneous ultrasound guidance, but biopsies using EUS have rarely been reported. In this report, we describe a case...
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Management of Women with Antiphospholipid Antibodies or Antiphospholipid Syndrome during Pregnancy

Lee EE, Jun JK, Lee EB

Antiphospholipid syndrome (APS), which is characterized by the presence of antiphospholipid antibodies (aPL), is associated with increased risk of thrombosis and obstetric complications, including preterm delivery and recurrent pregnancy losses....
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Aspirin and Non-steroidal Anti-inflammatory Drugs in Prevention of Gastric Cancer

Kim YJ, Chung WC

  • KMID: 2509972
  • J Dig Cancer Res.
  • 2020 Dec;8(2):77-80.
Gastric cancer is one of the leading causes of cancer-related deaths worldwide. The increased expression of cyclooxygenase (COX)-2 has been implicated in the development and progression of gastric cancers. A...
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Long-Term Aspirin Use and 5-Year Survival in Healthy Adults: A Population-Based Cohort Study in South Korea

Oh TK, Song IA

Purpose: We investigated whether long-term aspirin use is associated with 5-year all-cause mortality. Materials and Methods: Participants were individuals aged ≥40 years who were registered in the 2010 sample cohort database...
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Management of Peptic Ulcer Bleeding in Patients Taking Aspirin or Anticoagulant

Yang HJ

Antiplatelet and anticoagulation agents are increasingly prescribed for secondary prophylaxis in patients with cardiovascular and cerebrovascular diseases. These drugs are associated with an increased risk of gastrointestinal bleeding, including peptic...
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Prevention of Peptic Ulcer Associated with Aspirin and Antiplatelet Agent

Ahn JY

The Korean guidelines for the Clinical Guidelines for Drug-related Peptic Ulcer were revised under the Korean College of Helicobacter and Upper Gastrointestinal Research in 2020. In these revised guidelines, treatment...
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Helicobacter pylori Eradication in Drug-related Peptic Ulcer

Joo MK

Non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin are the most frequently prescribed drugs worldwide, and their long-term use often leads to peptic ulcers (PUs) along with serious complications, such as bleeding...
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Diagnosis and management of Kawasaki disease

Roh DE, Kwon JE, Kim YH

Kawasaki disease, also known as mucocutaneous lymph node syndrome, is a common form of vasculitis in childhood. Among the recent trends in Kawasaki disease, it is notable that the prevalence...
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Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of Helicobacter pylori Eradication and Aspirin

Watari J, Tomita T, Tozawa K, Oshima T, Fukui H, Miwa H

Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of...
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Epigenetic Changes in Asthma: Role of DNA CpG Methylation

Bae DJ, Jun JA, Chang HS, Park JS, Park CS

For the past three decades, more than a thousand of genetic studies have been performed to find out the genetic variants responsible for the risk of asthma. Until now, all...
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