Clin Psychopharmacol Neurosci.  2020 Feb;18(1):167-169. 10.9758/cpn.2020.18.1.167.

Ramelteon for Delayed Sleep-wake Phase Disorder: A Case Report

  • 1Department of Neuropsychiatry, Akita University Graduate School of Medicine
  • 2Mental Health and Welfare Center
  • 3Department of Neuropsychiatry, Nakadori Rehabilitation Hospital, Akita, Japan


Recently developed melatonin receptor agonists are expected to be effective for delayed sleep-wake phase disorder (DSWPD). To date, however, no study has described the effect of melatonin receptor agonists on DSWPD. We report the case of a 15-year-old girl with DSWPD who was successfully treated with ramelteon 4 mg at 7 PM. DSWPD symptoms were resolved; her sleep-wake and biological rhythms were normalized.


Circadian rhythm sleep disorders; Sleep disorders, circadian rhythm; Melatonin; Sleep wake disorders
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