Korean J Med.  2020 Apr;95(2):89-94. 10.3904/kjm.2020.95.2.89.

Osteoporosis in Patients with Chronic Kidney Disease

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea

Abstract

Osteoporosis in chronic kidney disease (CKD) is also referred to as ‘CKD with low bone mineral density (BMD)’, because the cause of low BMD in CKD includes chronic kidney disease-mineral bone disorders (CKD-MBD) such as secondary hyperparathyroidism, osteomalacia, and adynamic bone disease. Diagnostic methods of osteoporosis in CKD include FRAX®, BMD, and bone turnover markers as well as CKD-MBD biochemical parameters- calcium, P, alkaline phosphatase, PTH, and 25(OH)D3. The management of osteoporosis in CKD prioritizes CKD-MBD management over selection of bone anti-resorptive agents or osteo-anabolic agents according to clinical and laboratory findings.

Keyword

만성 신부전; 만성 콩팥병; 골다공증; 만성 콩팥병-미네랄뼈질환; Chronic kidney failure; Chronic kidney insufficiency; Osteoporosis; Chronic kidney disease mineral bone disorder
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