J Korean Orthop Assoc.  1975 Mar;10(1):13-16. 10.4055/jkoa.1975.10.1.13.

Clinical Observation on 18 Cases of Giant Cell Tumor

• Han SH

• KMID: 2471439
• DOI: http://doi.org/10.4055/jkoa.1975.10.1.13

Abstract

Giant cell tumor is a neoplasm, arising from the non bone forming. supporting connective tissue of marrow. The tumor is composed of a vascularized network of spindle shaped or ovoid stromal cell regularly and rather heavily interspersed with multinuclear cell. Giant cell tumor is one of the highly recurrent Bone tumor, which has predilection for epiphysis of long bone in skeletally mature patient. Clinical observation was carried out on 18 cases of giant cell tumor in the Department of orthopedic Surgery College of medicine, Seoul National University from Nov. 195$ through Jun 1974. The results were summarized as follows: 1) Giant cell tumor was rare, consisting of 22.9% of the cases of primary malignant tumors of bone. 2) The peak incidence was in the age group from 20 to 29 years in 9 cases (50%). 3) The sex distribution was 11 in males and 7 in females. 4) The most commonly affected sites were proximal tibia (5 CSS) and around the knee (cases, 50%). 5) Radical curettage and bone chip graft were performed as the treatment of 10 cases. 6) Postoperatively some patients were complicated with recurrence, infection and pathological fracture.

MeSH Terms

Bone Marrow
Connective Tissue
Curettage
Epiphyses
Female
Fractures, Spontaneous
Giant Cell Tumors*
Giant Cells*
Humans
Incidence
Knee
Male
Orthopedics
Recurrence
Seoul
Sex Distribution
Stromal Cells
Tibia
Transplants

Reference

1). Aegerter E.1968. Orthopedic disease. 3rd edition.W. B. Saunders Co.

2). Dahlin D. C.1970. Quoted by Goldenberg R. R.; Giant Cell Tumor of. Bone,. J. Bone and Joint Swvg. 52-A:619. June.

3). Gamerson G.W.1955. Giont Cell Tumor of the Patella. J. Bone and Joint Sarg. 37-A:184. Jon.

4). Goldenberg R. R.., Campbell C. J.1970. Giont Cell Tumor of Bone,. J. Bone and Joint Surg. 52-A:619. June.

5). Golding C.1966. Radiology and Orthopaedic Surgery. J. Bone and Joint Surg. 48-B:320.

6). Jaffe H. L.1958. Tumors and Tumerous Coudions of the Bones and Joints. Philadelphia, Lea and Febiger.

7). Jewell J. H.., Bush L. F.1964. Benign Giont Cell Tumor of Bone with a Solitary Pulmonary Metastasis. J. Bone and Joint Surg. 46-A:848.

8). Johnson E. W.., Dahling D. C.1959. Treatment of Giont Cell Tumor of Bone. J. Bone and Joint Surg. 41-A:895.

9). Lichtenstein L.1972. Bone Tumors. 4th edition.The C. V. Mosby Co..

10). Mnaymneh W. A.., Dudley H. R.1964. Giont Cell Tumor of Bone. An Analysis and Follow up Study of the Forty-one Cases. J. Bone and Joint Surg. 46-A:63. Jon.

11). Parrish F. F.1966. Treatement of Bone Tumors by Total Excision and Replacement with Massive Autologous and Homologous Grafts. J. J. Bone and Joint Surg. 48-A:968.

12). Pymble P. J. M.1972. Giont Cell Tumor of Bone An Analysis of Fifty-two Cases. J Bone and Joint Surg. 54-B:216.

13). Riley L. H.., Hartmann W. H.., Robinson R. A.1967. Soft Tissue Recurrence of Giont Cell Tumor of Bone after Irradiation and Excision,. J. Bone and Joint Surg. 49-A:365. Mar.

14). Schajowicz F.1961. Giont Cell Tumors of Borne A Pathological and Histochemical Study. J. Bone and Joint Surg. 43-A:1.

15). Schajowicz F.1966. Giont Cell Tumor Associated with Paget'sdisease of Bone, A Case Report. J. Bone and Joint Surg. 48-A:1340.

16). Thomsou A. D.., Turner-Warwick R. T.1955. Skeletal Sarcomata and Giont Cell Tumor. J. Bone and Joint Surg. 37-B:226.

17). Wearne W. M.1968. Giont Cell Timor of Bone. J. Bone and Joint Surg. 50-B:676.