Int J Oral Biol.  2019 Dec;44(4):191-194. 10.11620/IJOB.2019.44.4.191.

Antimicrobial effect of Australia propolis on cariogenic and periodontopathic bacteria

Affiliations
  • 1Korean Collection for Oral Microbiology, College of Dentistry, Chosun University, Gwangju 61452, Republic of Korea. jkkook@chosun.ac.kr
  • 2Department of Oral Biochemistry, College of Dentistry, Chosun University, Gwangju 61452, Republic of Korea.
  • 3Medi Bio Lab Co., Ltd., Seoul 08389, Republic of Korea. dsl2008@naver.com

Abstract

The purpose of this study was to investigate the antimicrobial effects of Australia propolis against cariogenic and periodontopathic bacteria. Antimicrobial activity was determined by evaluating the minimal bactericidal concentration (MBC). Cell cytotoxicity of propolis extract on normal human gingival fibroblast (HGF-1) cells was observed using the methylthiazolyldiphenyl-tetrazolium bromide assay. The data indicated that, with the exception of Aggregatibacter actinomycetemcomitans (KCOM 1306), the MBC values of the propolis strains were 0.25-1% without HGF-1 cell cytotoxicity. These results suggest that propolis can be used to develop oral hygiene products for the prevention of oral infectious disease.

Keyword

Antimicrobial effect; Dental caries; Periodontitis; Propolis
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