J Korean Orthop Assoc.  1972 Dec;7(4):405-411. 10.4055/jkoa.1972.7.4.405.

Clinical Study of Steroid Induced Side Effects in Orthopedic Field

Abstract

Clinical study of 40 cases who have used steroid preparations was done during past 6 months from March 72 to September 72. 1. The youngest patient was twenty, the oldest seventy-four and the average fifty-two. Eighty percent was included between from 41 to 70 year of age. 2. And the sex ratio was 1:4.7. 3. Diagnostic incidence was 47.5% in degenerative arthritis and 40% in rheumatoid arthritis. 4. The causes of administration were multiple joint pain (35%), lumbago (27.5%) and pain on knee joint (25%) in order. 5. Prednisolone (60%), dexacortisil (25%) and dexamethasone (12.5%) were used in 97.5%. 6. The source of steroid was drung store (95%) or doctor (5%). 7. The time from first dose to last dose was less than 1month (20%), 1-3 month(10%), 4-6 month (7.5%) and more than 1 year (52.5%). And 3 cases have used for more than 5 years, 8. Eighteen cases (45%) used steroid continuously and 22 cases (55%) irregularly. 9. Transient effectiveness was experienced in 92.5% with steroid administration, that was one of the causes of steroid usage without doctor's prescription. 10. The side effects were as follows; moon face (62.5%), ulcer (20%), fat deposition (15%), osteoporosis (15%), peripheral edema (10%), elevation of blood pressure (7.5%), malar flush(7.5%), vertebral compression fracture (7.5%), obesity (5%), psychotic change (5%), pyogenic arthritis (5%), diabetes (2.5%), sepsis (2.5%), adrenal insufficiency (2.5%), avascular necrosis (2.5%) and stress fracture of femur neck (2.5%).


MeSH Terms

Adrenal Insufficiency
Arthralgia
Arthritis
Arthritis, Rheumatoid
Blood Pressure
Clinical Study*
Dexamethasone
Edema
Femur Neck
Fractures, Compression
Fractures, Stress
Humans
Incidence
Knee Joint
Low Back Pain
Moon
Necrosis
Obesity
Orthopedics*
Osteoarthritis
Osteoporosis
Prednisolone
Prescriptions
Sepsis
Sex Ratio
Ulcer
Dexamethasone
Prednisolone
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