Asia Pac Allergy.  2019 Oct;9(4):e29. 10.5415/apallergy.2019.9.e29.

Chlorhexidine: a hidden life-threatening allergen

Affiliations
  • 1Serviço de Imunoalergologia, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte EPE, Portugal. maravfernandes@gmail.com
  • 2Unidade de Imunoalergologia, Hospital Dr. Nélio Mendonça, SESARAM EPE, Funchal, Portugal.
  • 3Laboratório de Imunologia Clínica, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Portugal.
  • 4Clínica Universitária de Imunoalergologia, Faculdade de Medicina da Universidade de Lisboa, Portugal.

Abstract

Chlorhexidine is a commonly used antiseptic and disinfectant in the health-care setting. Anaphylaxis to chlorhexidine is a rare but potentially life-threatening complication. Epidemiologic data suggest that the cases of chlorhexidine allergy appears to be increasing. In this article we report a life-threatening anaphylactic shock with cardiorespiratory arrest, during urethral catheterization due to chlorhexidine. The authors also performed a literature review of PubMed library of anaphylactic cases reports due to this antiseptic between 2014 and 2018, demonstrating the increase in the number of cases occurring worldwide and the importance of detailed anamnesis and appropriate diagnostic workup of allergic reactions to disinfectants.

Keyword

Allergy; Anaphylaxis; Chlorhexidine

MeSH Terms

Anaphylaxis
Chlorhexidine*
Disinfectants
Hypersensitivity
Urinary Catheterization
Urinary Catheters
Chlorhexidine
Disinfectants
Full Text Links
  • APA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr