Diabetes Metab J.  2019 Feb;43(1):46-48. 10.4093/dmj.2019.0027.

Concern about the Safety of Bisphenol A Substitutes

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mkmoon@snu.ac.kr
  • 2Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea.

Abstract

No abstract available.


Figure

  • Fig. 1 Chemical structures of (A) bisphenol A, (B) bisphenol S, and (C) bisphenol F.

  • Fig. 2 Profiling of bisphenol A (BPA) and eight its analogues on transcriptional activity via human nuclear receptors. Adapted from Kojima et al. [12], with permission from Elsevier. ERα, human estrogen receptors α; ERβ, human estrogen receptors β; AR, androgen receptor; GR, glucocorticoid receptor; PXR, pregnane X receptor; CAR, constitutive androstane receptor; REC20, the concentrations of the compound equal to 20% of the maximal response of the positive control intensity; RIC20, the concentrations of the test compounds showing 20% inhibition of the activities induced by the endogenous hormones or vehicle control.


Reference

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