Chonnam Med J.  2018 Jan;54(1):80-82. 10.4068/cmj.2018.54.1.80.

De Novo CD5-Positive Primary Gastric Diffuse Large B-Cell Lymphoma Coexpressing MYC and BCL6: Towards a Proper Subset of Double-Hit, Triple-Hit and, Maybe, Quadruple-Hit B-Cell Lymphomas?

Affiliations
  • 1Department of Diagnostic and Clinical Medicine and of Public Health, Institute of Pathology, University of Modena and Reggio Emilia, Modena, Italy. emailmedical@gmail.com

Abstract

No abstract available.


MeSH Terms

B-Lymphocytes*
Lymphoma, B-Cell*

Figure

  • FIG. 1 The large B-cell lymphoma arises in the stomach (A, hematoxylin & eosin; 4×), it shows a diffuse pattern of growth (B, hematoxylin & eosin; 10×), it is immunoreactive for CD20 (C, clone L26, Ventana; 4×) but not for CD3 (D, clone 2GV6, Ventana; 4×), it shows a high Ki67 labeling index (E, clone 30-9, Ventana; 10×) and coexpresses CD5 (F, clone SP19, Ventana; 4×), Myc (G, clone Y69, Ventana; 4×) and Bcl6 (H, clone GI191E/A8, Ventana; 4×).


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