J Korean Orthop Assoc.  1982 Feb;17(1):1-11. 10.4055/jkoa.1982.17.1.1.

Histological Changes Induced by Neurolysis: An Experimental Study on Rabbit Sciatic Nerve

• Ahn JH
• Yoo MC
• Kang SH
• Lee YG

• KMID: 2457903
• DOI: http://doi.org/10.4055/jkoa.1982.17.1.1

Abstract

Several attempts have been made to assess the relative importance of the vasa nervorum and the intrinsic longitudinal vascular plexuses of nerve in maintaining the blood supply of a segment of nerve trunk, but the effect of mobilization on the ability of an injuried or repaired nerve to regenerate and regain function has been less certain and is the subject of these investigations. Thirty-two Korean rabbits of both sexes were used for these studies and we concluded that it is increased fibrosis with adhesion to surrounded tissues, loss of glistening and milk-like discoloration of never grossly, and increased degeneration and milk-like discoloration of nerve grossly, and increased degeneration of axons and demyelization progressively and early proliferated Schwann cells with increasing length of neurolysis. And there was no recovery of damage in nerve tissue induced by above 7 cm of neurolysis. (1:35)

Keyword

Neurolysis; Histologic changes; Sciatic nerve

MeSH Terms

Axons
Fibrosis
Nerve Tissue
Rabbits
Schwann Cells
Sciatic Nerve*
Vasa Nervorum