J Pathol Transl Med.  2019 Jul;53(4):270-272. 10.4132/jptm.2018.12.17.

Endocervical Adenocarcinoma In Situ Phenotype with Ovarian Metastasis

• Kim HS
• Chung YS
• Kim MS
• Ryu HJ
• Lee JH

• KMID: 2454608
• DOI: http://doi.org/10.4132/jptm.2018.12.17

Abstract

No abstract available.

MeSH Terms

Adenocarcinoma in Situ*
Adenocarcinoma*
Neoplasm Metastasis*
Phenotype*

Figure

• 

  Fig. 1. (A) Histological findings of the endocervical lesion. Endocervical adenocarcinoma in situ (AIS) extensively involves the endocervix. No cervical stromal invasion is identified. (B–D) Histological findings of the ovarian lesion. The tumor displays a well-differentiated glandular architecture with primarily (B) endometrioid-like and focally (C) mucinous differentiation. (D) High-power magnification of the ovarian lesion reveals enlarged and hyperchromatic nuclei with intracytoplasmic mucin vacuoles, mitotic figures, and apoptotic bodies, similar to those of the endocervical AIS. (E, F) p16 immunostaining results. Both the (E) endocervical and (F) ovarian lesions show strong and diffuse p16 immunoreactivities.

Reference

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