Ultrasonography.
2019 Jul;38(3):246-254. 10.14366/usg.18046.
Reproducibility of liver stiffness measurements made with two different 2-dimensional shear wave elastography systems using the comb-push technique
- Affiliations
-
- 1Department of Radiology, Pusan National University Yangsan Hospital, Yangsan, Korea.
- 2Department of Radiology, Gachon University Gil Medical Center, Incheon, Korea.
- 3Department of Radiology, Seoul National University Hospital, Seoul, Korea. jmsh@snu.ac.kr
- 4Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
- 5Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.
- KMID: 2452551
- DOI: http://doi.org/10.14366/usg.18046
Abstract
- PURPOSE
The purpose of this study was to retrospectively compare the technical success and reliability of the measurements made using two 2-dimensional (2D) shear wave elastography (SWE) systems using the comb-push technique from the same manufacturer and to assess the intersystem reproducibility of the resultant liver stiffness (LS) measurements.
METHODS
Ninety-four patients with suspected chronic liver diseases were included in this retrospective study. LS measurements were obtained using two 2D-SWE systems (LOGIQ E9 and LOGIQ S8) from the same manufacturer, with transient elastography (TE) serving as the reference standard, on the same day. The technical success rates and reliability of the measurements of the two 2D-SWE systems were compared. LS values measured using the two 2D-SWE systems and TE were correlated using Spearman correlation coefficients and 95% Bland-Altman limits of agreement. Thereafter, Bland-Altman limits of agreement and intraclass correlation coefficients (ICCs) were used to analyze the intersystem reproducibility of LS measurements.
RESULTS
The two 2D-SWE systems showed similar technical success rates (98.9% for both) and reliability of LS measurements (92.3% for the LOGIQ E9, 91.2% for the LOGIQ S8; P=0.185). Despite the excellent correlation (ICC=0.92), the mean LS measurements obtained by the two 2D-SWE systems were significantly different (LOGIQ E9, 6.57±2.33 kPa; LOGIQ S8, 6.90±6.64 kPa; P=0.018).
CONCLUSION
Significant intersystem variability was observed in the LS measurements made using the two 2D-SWE systems. Therefore, even 2D-SWE systems from the same manufacturer should not be used interchangeably in longitudinal follow-up.
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