Clin Endosc.  2019 May;52(3):220-225. 10.5946/ce.2018.094.

Endoscopic Ultrasound-Guided Biliary Drainage for Unresectable Hilar Malignant Biliary Obstruction

  • 1Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Japan.
  • 2Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.


Endoscopic transpapillary biliary drainage is the current standard of care for unresectable hilar malignant biliary obstruction (MBO) and bilateral metal stent placement is shown to have longer patency. However, technical and clinical failure is possible and percutaneous transhepatic biliary drainage (PTBD) is sometimes necessary. Endoscopic ultrasound-guided biliary drainage (EUS-BD) is increasingly being reported as an alternative rescue procedure to PTBD. EUS-BD has a potential advantage of not traversing the biliary stricture and internal drainage can be completed in a single session. Some approaches to bilateral biliary drainage for hilar MBO under EUS-guidance include a bridging method, hepaticoduodenostomy, and a combination of EUS-BD and transpapillary biliary drainage. The aim of this review is to summarize data on EUS-BD for hilar MBO and to clarify its advantages over the conventional approaches such as endoscopic transpapillary biliary drainage and PTBD.


Biliary drainage; Endosonography; Hilar biliary obstruction; Neoplasms

MeSH Terms

Constriction, Pathologic
Standard of Care


  • Fig. 1. Techniques of bilateral endoscopic ultrasound-guided biliary drainage. (A) Bridging method. (B) Endoscopic ultrasound-guided hepaticoduodenostomy. (C) Combined endoscopic ultrasound-guided hepaticogastrostomy and transpapillary stenting.

  • Fig. 2. Bridging method. (A) Endoscopic ultrasound-guided hepaticogastrostomy was performed during the first session. (B) A bridging stent was placed during the second session.

  • Fig. 3. Combined endoscopic ultrasound-guided hepaticogastrostomy and transpapillary stenting. (A) Endoscopic ultrasound-guided hepaticogastrostomy was performed during the first session. (B) Transpapillary multiple stent-in-stent placement was performed during the second session.

Cited by  3 articles

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Korean J Gastroenterol. 2021;78(2):94-104.    doi: 10.4166/kjg.2021.111.

What You Need to Know Before Performing Endoscopic Ultrasound-guided Hepaticogastrostomy
Tanyaporn Chantarojanasiri, Thawee Ratanachu-Ek, Nonthalee Pausawasdi
Clin Endosc. 2021;54(3):301-308.    doi: 10.5946/ce.2021.103.

Endoscopic Biliary Drainage for Hilar Obstruction: Further Evidence But Still A Long Way To Go
Yousuke Nakai
Clin Endosc. 2021;54(5):629-630.    doi: 10.5946/ce.2021.158.


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