Korean J Otorhinolaryngol-Head Neck Surg.  2019 Apr;62(4):250-254. 10.3342/kjorl-hns.2017.01102.

Two Cases of Recurrent Nasal Polyps in Siblings-Woakes' Syndrome

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea. doncamel@dau.ac.kr

Abstract

Woakes' syndrome is a group of disease which include recurrent nasal polyps resulting in the broadening of the nasal pyramid, the onset of hypoplasia of frontal sinus and bronchiectasis, as well as the production of mucous discharge. Children and young adults are mostly susceptible to Woakes' syndrome due to the plasticity of the bone. Even though the exact etiology is unknown, genetic factor is thought to be influential because it is often diagnosed in siblings. Otolaryngologically, the mainstream method of removing nasal polyp by endoscopic sinus surgery as well as topical or systemic treatment can be helpful. We report two siblings who visited our clinic both complaining of nasal obstruction. The patients presented with recurrent nasal polyps and showed signs of bronchiectasis, which led to the diagnosis of Woakes' syndrome. These rare cases are presented here with a review of related literature.

Keyword

Bronchiectasis; Endoscopic sinus surgery; Nasal polyp; Woakes' syndrome

MeSH Terms

Bronchiectasis
Child
Diagnosis
Fibrinogen
Frontal Sinus
Humans
Methods
Nasal Obstruction
Nasal Polyps*
Plastics
Siblings
Young Adult
Fibrinogen
Plastics
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