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Exacerbation Prevention and Management of Bronchiectasis

Choi JY

Bronchiectasis, which is characterized by irreversibly damaged and dilated bronchi, causes significant symptoms, poor quality of life, and increased economic burden and mortality rates. Despite its increasing prevalence and clinical...
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Prevalence of chronic rhinosinusitis and its relating factors in patients with bronchiectasis: findings from KMBARC registry

Yu I, Yong SJ, Lee WY, Kim SH, Lee H, Na JO, Kim DK, Oh YM, Lee JH, on behalf of the KMBARC

Background/Aims: Patients with bronchiectasis often present with respiratory symptoms caused by chronic rhinosinusitis (CRS). However, studies on the prevalence of CRS and its relationship with bronchiectasis are limited. Methods: The baseline...
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Diagnosis and Management of Comorbidities Associated with Bronchiectasis

Choi H, Lee H

Patients with non-cystic fibrosis bronchiectasis (hereafter referred to as bronchiectasis) often present with comorbidities. These comorbidities significantly impact symptoms, acute exacerbation, hospitalization, disease progression, and mortality in patients with bronchiectasis....
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Developing a Diagnostic Bundle for Bronchiectasis in South Korea: A Modified Delphi Consensus Study

Choi H, Lee H, Ra SW, Jang JG, Lee JH, Jhun BW, Park HY, Jung JY, Lee SJ, Jo KW, Rhee CK, Kim C, Lee SW, Min KH, Kwon YS, Kim DK, Lee JH, Park YB, Chung EH, Kim YJ, Yoo KH, Oh YM

Background: Because the etiologies of bronchiectasis and related diseases vary significantly among different regions and ethnicities, this study aimed to develop a diagnostic bundle for bronchiectasis in South Korea. Methods: A...
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Efficacy of Roflumilast in Bronchiectasis Patients with Frequent Exacerbations: A Double-Blinded, Randomized, Placebo-Controlled Pilot Clinical Trial

Juthong S, Panyarath P

Background: Bronchiectasis patients with neutrophilic airway inflammation develop symptoms of chronic cough, sputum production, and recurrent exacerbations. Roflumilast has anti-inflammatory actions via decreased neutrophilic airway inflammation. The effectiveness of roflumilast...
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Survey of the management of patients with bronchiectasis: a pilot investigation in Asian populations

Kim HC, Suzuki M, Lim HF, Lan LTT, Nguyen HL, Wang JS, Lee KY, Lee JS, Oh YM, Lee SD, Choi H, Lee H, Lee SW

Background/Aims: Although international guidelines for bronchiectasis management have been published in Western countries, there is a lack of data about their application in Asian populations including patients with different phenotypes....
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Respiratory Viruses in Acute Exacerbations of Bronchiectasis

Park YE, Sung H, Oh YM

Background: Bacterial infections are well known factors underlying acute exacerbations in bronchiectasis. However, viral infections may also contribute to acute exacerbations. We aimed to assess the rate of viral detection...
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Spectrum of Pulmonary Fibrosis from Interstitial Lung Abnormality to Usual Interstitial Pneumonia: Importance of Identification and Quantification of Traction Bronchiectasis in Patient Management

Hino T, Lee KS, Han J, Hata A, Ishigami K, Hatabu H

Following the introduction of a novel pathological concept of usual interstitial pneumonia (UIP) by Liebow and Carrington in 1969, diffuse interstitial pneumonia has evolved into UIP, nonspecific interstitial pneumonia (NSIP),...
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Nontuberculous mycobacterial pulmonary disease in a 16-year-old female patient with bronchiectasis

Song Ys, Jeong Hi, Lee Br, Huh Hj, Koh Wj, Kim Jh, Ahn Km, Kyung Yc

Nontuberculous mycobacterial (NTM) pulmonary disease generally occurs in old people with underlying lung disease. However, unlike adults, NTM infections in children with normal immunity are rare, and they occasionally manifest...
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Update on pharmacotherapy for adult bronchiectasis

Choi H, Lee H, Ra SW, Oh YM

Bronchiectasis refers to abnormal dilatation of the bronchi, which leads to the failure of mucus clearance and increased risk of infection. Pharmacotherapy for stable bronchiectasis includes oral or inhaled mucoactive...
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Validation of the Korean Version of the Bronchiectasis Health Questionnaire

Kim HK, Lee H, Kim SH, Choi H, Lee JH, Lee JS, Lee SW, Oh YM

Background: The Bronchiectasis Health Questionnaire (BHQ) is a simple and repeatable, self-reporting health status questionnaire for bronchiectasis. We have translated the original version of the BHQ into Korean using a...
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Clinical Approach to Non-cystic fibrosis Bronchiectasis Based on Recent Clinical Guideline

Lee H, Oh YM

Non-cystic fibrosis bronchiectasis is a common respiratory disease that is frequently encountered in daily practice. However, it has been regarded as an orphan lung disease and had been often neglected...
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A Child who has Nasal Polyposis Combined with Bronchiectasis

Kim S, Kim D, Bae WY, Jung JA

Nasal polyps are inflammatory lesions of sinonasal tissue that are associated with chronic rhinosinusitis, allergic reaction, and other diseases. Although it is the most common cause of nasal polyps, chronic...
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Impact of Bronchiectasis on Postoperative Pulmonary Complications after Extra-Pulmonary Surgery in Patients with Airflow Limitation

Yang B, Choi H, Chung SJ, Shin B, Lee H, Park HY

The impact of bronchiectasis on the occurrence of postoperative pulmonary complications (PPC) after extra-pulmonary surgery in patients with airflow limitation is not well elucidated. A retrospective analysis of 437 patients...
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Two Cases of Recurrent Nasal Polyps in Siblings-Woakes' Syndrome

Lee CB, Jung NY, Loh YJ, Bae WY

Woakes' syndrome is a group of disease which include recurrent nasal polyps resulting in the broadening of the nasal pyramid, the onset of hypoplasia of frontal sinus and bronchiectasis, as...
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Bronchiectasis and Recurrent Respiratory Infections with a De Novo STAT1 Gain-of-Function Variant: First Case in Korea

Huh HJ, Jhun BW, Choi SR, Kim YJ, Yun SA, Nham E, Kong T, Ki CS, Koh WJ

Bronchiectasis is a chronic disease characterized by airway infection and inflammation, leading to permanent dilation of the bronchi. Evaluation of underlying etiology is important in managing young bronchiectasis patients with...
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Literature review and future strategies of childhood respiratory diseases in Korea

Han MY, Chung HL, Ahn YM, Shim JY

Thirty years have passed since the Korean Association of Pediatric Allergy and Respiratory Disease was founded. There have been great changes in the pattern of respiratory diseases in Korean children...
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Conjunction of a Fungus Ball and a Pulmonary Tumourlet in a Bronchiectatic Cavity

Yazgan S, Gürsoy S, Türk F, Dinç ZA

Herein, we describe the case of a 67-year-old female patient who presented with cough and haemoptysis. Chest computed tomography revealed destruction of the left lower lobe and multiple fungus balls...
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A review of 42 asthmatic children with allergic bronchopulmonary aspergillosis

Shah A, Kunal S

BACKGROUND: Allergic bronchopulmonary aspergillosis (ABPA) in children with asthma, not associated with cystic fibrosis, is yet to receive the recognition it deserves. OBJECTIVE: To highlight the presentation of ABPA in children...
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Delayed diagnosis of allergic bronchopulmonary aspergillosis due to absence of asthmatic symptoms

Kim Y, Lee HY, Gu KM, Lee JY, Yoon SW, Park TY, Choi JC, Kim JY, Park IW, Shin JW, Choi BW, Jung JW

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease with small prevalence. Exposure to aspergillus mold causes immunologic hypersensitivity and may cause ranges of symptoms from minimal to detrimental outcomes. Diagnosing...
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