Kosin Med J.  2018 Dec;33(3):283-288. 10.7180/kmj.2018.33.3.283.

The ideal strategies of chemotherapy for the treatment of cervical cancer

• Koh SB

• KMID: 2442538
• DOI: http://doi.org/10.7180/kmj.2018.33.3.283

Abstract

Historically, the standard treatment for early-stage cervical cancer has been radical surgery in patients with operable disease. Patients with locally advanced disease (defined as FIGO stage IB2 and usually with tumors greater than 4 cm, IIB, III and IVA) are usually treated with radical radiotherapy, which consists of external beam radiotherapy and internal brachytherapy. However, the discovery that cervical cancer tumors are sensitive to chemotherapy led to the initiation of studies looking at adding chemotherapy to both radiotherapy and surgery. Following a National Cancer Institute (NCI) alert in 1999 (NCI 1999), chemoradiotherapy became the standard of care for women with locally advanced cervical cancer.

Keyword

Cervical cancer; Chemotherapy

MeSH Terms

Brachytherapy
Chemoradiotherapy
Drug Therapy*
Female
Humans
National Cancer Institute (U.S.)
Radiotherapy
Standard of Care
Uterine Cervical Neoplasms*