J Korean Diabetes.  2019 Mar;20(1):17-23. 10.4093/jkd.2019.20.1.17.

Diagnosis of Peripheral Artery Disease: Focus on the 2016 American Heart Association/American College of Cardiology and 2017 European Society of Cardiology Guidelines

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ky.hur@samsung.com

Abstract

Peripheral artery disease (PAD) is the most frequent cause of reduced perfusion in peripheral arteries. Patients with PAD often have manifestations of atherosclerosis of the lower limb, although both symptomatic and asymptomatic disease is common. The clinical signs of PAD can differ in diabetic and non-diabetic patients. Diabetic patients are at high risk for PAD characterized by symptoms of intermittent claudication or critical limb ischemia. However, the majority of PAD patients are clinically asymptomatic. In addition to history taking, physical examinations including inspection of the skin, palpation of leg and foot pulses, and determination of the ankle-brachial index (ABI) are considered for diagnosis of PAD. The ABI measurement is the easiest and most common investigative technique for PAD. For hemodynamic assessment, additional diagnostic modalities could be considered.

Keyword

Ankle brachial index; Diabetes mellitus; Peripheral arterial disease

MeSH Terms

Ankle Brachial Index
Arteries
Asymptomatic Diseases
Atherosclerosis
Cardiology*
Diabetes Mellitus
Diagnosis*
Extremities
Foot
Heart*
Hemodynamics
Humans
Intermittent Claudication
Investigative Techniques
Ischemia
Leg
Lower Extremity
Palpation
Perfusion
Peripheral Arterial Disease*
Physical Examination
Skin

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