Korean J Vet Res.  2018 Mar;58(1):45-49. 10.14405/kjvr.2018.58.1.45.

Detection and characterization of avian hepatitis E virus from broiler breeders and layers in Korea

• Moon HW
• Sung HW
• Kwon HM

• KMID: 2437677
• DOI: http://doi.org/10.14405/kjvr.2018.58.1.45

Abstract

The helicase genes and hypervariable regions (HVRs) of three avian hepatitis E viruses (HEVs) detected at three different farms were sequenced and characterized. Two isolates (DW-L and GI-B2) were classified as genotype 2 and one isolate (GR-B) was classified as genotype 1. A phylogenetic tree, based on the helicase gene and HVR nucleotide sequences, revealed the newly detected viruses and other avian HEVs were classified similarly. Unlike previously reported avian HEVs, the DW-L isolate detected in broiler breeders with characteristic lesions of avian HEV had no prolinerich motif in its HVR, suggesting that the proline-rich motif is non-essential for viral replication and infection.

Keyword

avian hepatitis E virus; helicase gene; hypervariable region; sequences

MeSH Terms

Agriculture
Base Sequence
Genotype
Hepevirus*
Korea*
Trees