Keimyung Med J.  2018 Jun;37(1):9-16. 10.0000/kmj.2018.37.1.9.

Optimal Concentration of Sufentanil for Patient Controlled Epidural Analgesia in Gastrectomy

• Oh JH
• Park KB
• Park EK
• Bae JH
• Kim HJ
• Lee JW
• Hong JH

• KMID: 2437655
• DOI: http://doi.org/10.0000/kmj.2018.37.1.9

Abstract

Patient controlled epidural anlagesia is a commonly used method for postoperative pain management. The purpose of this study is to determine the optimal concentration of sufentanil for patient controlled epidural analgesia. Twenty eight patients who underwent elective gastrectomy were enrolled in this study. Patients were randomly assigned to one of two groups of 0.5 µg/mL (group S1) and 0.7 µg/mL (group S2). At 2 hours, 1 day, 2 days and 3 days after surgery, the patient's pain degree was checked by numerical rating scale (NRS) and the presence of side effects was assessed. In both groups, the NRS decreased linearly with time. The NRS of the two groups differed but the trend of decrease did not show significant difference. The overall incidence of side effects was 45.5% (group S1) and 58.8% (group S2), respectively. Patient controlled epidural analgesia using sufentanil was effective in controlling postoperative pain, which was found to decrease with time. When comparing the two concentrations used in this study, 0.5 µg/mL had a lower incidence of side effects than the concentration of 0.7 µg/mL, and the pain relief trends of the two concentrations were similar.

Keyword

Epidural; Gastrectomy; Patient controlled analgesia; Sufentanil

MeSH Terms

Analgesia, Epidural*
Analgesia, Patient-Controlled
Gastrectomy*
Humans
Incidence
Methods
Pain, Postoperative
Sufentanil*
Sufentanil