Clin Pediatr Hematol Oncol.  2018 Oct;25(2):197-201. 10.15264/cpho.2018.25.2.197.

Two Pediatric Cases of Spontaneous Ruptured Solid Tumors Successfully Treated with Transcutaneous Arterial Embolization

Affiliations
  • 1Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, Korea. limyt@pusan.ac.kr
  • 2Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Abstract

Spontaneous rupture with internal bleeding of solid tumors has rarely been described at the time of diagnosis or during chemotherapy. This rare event must be regarded as a life threatening condition. In these emergency situations, control of hemorrhage, which is life-saving, can be achieved by transcatheter arterial embolization (TAE) and/or surgical resection. This report describes two infants presenting with acute hemorrhagic shock due to spontaneous tumor rupture of hepatoblastoma and neuroblastoma during chemotherapy. TAE successfully arrested the tumor bleeding and a visibly reduced the tumor size in both children. Spontaneous rupture of solid tumors occur infrequently in children, but is a life threatening situation. Careful monitoring for the occurrence of this rare event especially in very young children presenting with a large tumor mass.

Keyword

Ruptured solid tumor; Transcatheter arterial embolization; Children

MeSH Terms

Child
Diagnosis
Drug Therapy
Emergencies
Hemorrhage
Hepatoblastoma
Humans
Infant
Neuroblastoma
Rupture
Rupture, Spontaneous
Shock, Hemorrhagic
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