Ann Rehabil Med.  2018 Apr;42(2):358-362. 10.5535/arm.2018.42.2.358.

Botulinum Toxin Injection in the Treatment of Postextubation Dysphagia: A Case Report

Affiliations
  • 1Department of Rehabilitation Medicine, Dankook University College of Medicine, Cheonan, Korea. magnarbor@dankook.ac.kr
  • 2Department of Nanobiomedical Science & WCU Research Center, Dankook University, Cheonan, Korea.
  • 3Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Korea.

Abstract

Prolonged intubation is known to bring on postextubation dysphagia (PED) in some patients. We have noted that there were some studies to investigate specific type and pattern of PED, which showed large variety of different swallowing abnormalities as mechanisms of PED that are multifactorial. There are several options of treatment in accordance with the management of these abnormalities. A botulinum toxin (BoT) injection into the upper esophageal sphincter (UES) can improve swallowing functions for patients with this disorder, by working to help the muscle relax. In this case, the conventional treatment was not effective in patients with PED, whereas the BoT injection made a great improvement for these patients. This study suggests that the UES pathology could be the main cause of PED.

Keyword

Deglutition disorders; Endotracheal intubation; Botulinum toxin
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