Asian Oncol Nurs.  2018 Jun;18(2):55-65. 10.5388/aon.2018.18.2.55.

Comparison of Depression and Quality of Life according to Nutritional Status in Elderly Cancer Patients Receiving Chemotherapy

Affiliations
  • 1Department of Nursing, Asan Medical Center, Seoul, Korea.
  • 2Department of Clinical Nursing, University of Ulsan, Seoul, Korea. kimjh@amc.seoul.kr

Abstract

PURPOSE
The purpose of this study was to compare depression and quality of life (QOL) according to nutritional status of elderly cancer patients receiving chemotherapy.
METHODS
A sample of 144 elderly cancer patients receiving chemotherapy was recruited for the cross-sectional survey design. The instruments were the Mini Nutritional Assessment-Short Form (MNA-SF), Geriatric Depression Scale Short Form-Korea (GDSSF-K), European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ ELD14. Data were analyzed using the SPSS/WIN program.
RESULTS
Nutrition had mean of 10.17 points out of 14 and depression had mean of 6.72 points (out of 15). In quality of life, global health status/QoL was 50.06 points, 66.68 for the functional scale, and 29.77 for the symptom scale based on 100 points. The quality of life of elderly cancer patients was 36.52~70.14. There was a significant difference between the well-nourished and malnourished group in depression and QoL. There were significant correlations among the variables, nutritional status, depression and quality of life.
CONCLUSION
We found that patients with cancer of the elderly receiving chemotherapy had poor nutritional status, depression, and poor QoL. It is necessary to evaluate the nutritional status of elderly cancer patients receiving chemotherapy and to develop interventions.

Keyword

Aged; Nutrition Status; Depression; Quality of Life; Neoplasms

MeSH Terms

Aged*
Cross-Sectional Studies
Depression*
Drug Therapy*
Global Health
Humans
Nutritional Status*
Quality of Life*

Cited by  1 articles

Symptom Distress and Depression in Patients with Recurrent Gynecologic Cancer Undergoing Chemotherapy: Mediating Effect of Resilience
Eun Jung Yang, Ho Sihn Ryu
Korean J Adult Nurs. 2019;31(1):28-37.    doi: 10.7475/kjan.2019.31.1.28.


Reference

1. National Cancer Information Center (KR). Cancer statistics [Internet]. Available from. https://www.cancer.go.kr/lay1/S1T639C640/contents.do. [Accessed February 19, 2018].
2. Korea National Statistical Office. Future population estimation 2010–2060 [Internet]. Available from. http://kostat.go.kr/portal/korea/kor_nw/2/2/1/index.board?bmode=read&bSeq=&aSeq=252623&pageNo=1&rowNum=10&navCount=10&currPg=&sTarget=exp&sTxt=%E B%85%B8%EC%9D%B8. [Accessed May 19, 2017].
3. Park S, Hong J, Hwang I, Ahn JY, Cho EY, Park J, et al. Comprehensive geriatric assessment in elderly patients with newly diagnosed aggressive non-Hodgkin lymphoma treated with multi-agent chemotherapy. J Geriatr Oncol. 2015; 6:470–8.
Article
4. NCCN Clinical Practice Guidelines in Oncology (US). Older adult oncology [Internet]. Available from. https://www.nccn.org/store/login/login.aspx?ReturnURL=https. [Accessed May 19, 2017].
5. Kim MJ, Kim JW. Assessment of elderly cancer patients and its clinical importance. Korean J Obstet Gynecol. 2008; 51:691–706.
6. Lee HS, Kang JH, Kim EM, Kim WG. Prevalence of malnutrition in hospitalized elderly Korean patients based on mini nutritional assessment-short form. J Clin Nutr. 2014; 6:24–9.
Article
7. Mun JH. The relationships between nutritional status, fatigue and quality of life in elderly cancer patients receiving chemotherapy [dissertation]. Pusan: Kosin Univ.;2014.
8. Duc S, Rainfray M, Soubeyran P, Fonck M, Blanc JF, Ceccaldi J, et al. Predictive factors of depressive symptoms of elderly patients with cancer receiving first-line chemotherapy. Psychooncology. 2017; 26:15–21.
Article
9. Rasheed S, Woods RT. An investigation into the association between nutritional status and quality of life in older people admitted to hospital. J Hum Nutr Diet. 2014; 27:142–51.
Article
10. Wedding U, Pientka L, Höffken K. Quality-of-life in elderly patients with cancer: a short review. Eur J Cancer. 2007; 43:2203–10.
Article
11. Nestle Nutrition Institute (CH). MNA® mini nutritional assessment [Internet]. Available from. http://www.mna-elderly.com/. [Accessed May 19, 2017].
12. Ranhoff AH, Gj⊘en AU, Mowé M. Screening for malnutrition in elderly acute medical patients: the usefulness of MNA-SF. J Nutr Health Aging. 2005; 9:221–5.
13. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-1983; 17:37–49.
Article
14. Cho MJ, Bae JN, Suh GH, Hahm BJ, Kim JK, Lee DW, et al. Validation of geriatric depression scale, Korean version (GDS) in the assessment of DSM-III-R major depression. J Korean Neuropsychiatr Assoc. 1999; 38:48–63.
15. Yun YH, Park YS, Lee ES, Bang SM, Heo DS, Park SY, et al. Validation of the Korean version of the EORTC QLQ-C30. Qual Life Res. 2004; 13:863–8.
Article
16. Wheelwright S, Darlington AS, Fitzsimmons D, Fayers P, Arraras JI, Bonnetain F, et al. International validation of the EORTC QLQ-ELD14 questionnaire for assessment of health-related quality of life elderly patients with cancer. Br J Cancer. 2013; 109:852–8.
Article
17. Singh N, Singh PS, Aggarwal AN, Behera D. Comorbidity assessment using Charlson comorbidity index and simplified comorbidity score and its association with clinical outcomes during first-line chemotherapy for lung cancer. Clin Lung Cancer. 2016; 17:205–13.e1.
Article
18. Gajra A, Klepin HD, Feng T, Tew WP, Mohile SG, Owusu C, et al. Pre-dictors of chemotherapy dose reduction at first cycle in patients age 65 years and older with solid tumors. J Geriatr Oncol. 2015; 6:133–40.
19. Yanagi A, Murase M, Sumita YI, Taniguchi H. Investigation of nutritional status using the mini nutritional assessment-short form and analysis of the relevant factors in patients with head and neck tumour. Gerodontology. 2017; 34:227–31.
Article
20. Kee BS. A preliminary study for the standardization of geriatric depression scale short form-Korea version. J Korean Neuropsychiatr Assoc. 1996; 35:298–307.
21. Jee YJ, Lee YB. Factors influencing depression among elderly patients in geriatric hospitals. J Phys Ther Sci. 2013; 25:1445–9.
22. Kang IO, Yun YH. Preliminary investigation of the quality of life in the elderly with cancer. J Korean Acad Fam Med. 2004; 25:678–86.
23. Kim JH, Choi KS, Kim TW, Hong YS. Quality of life in colorectal cancer patients with chemotherapy-induced peripheral neuropathy. J Korean Oncol Nurs. 2011; 11:254–62.
Article
24. Goo AJ, Shin DW, Yang HK, Park JH, Kim SY, Shin JY, et al. Cross-cul-tural application of the Korean version of the EORTC QLQ-ELD14 questionnaire for elderly patients with cancer. J Geriatr Oncol. 2017; 8:271–6.
Article
25. Nho JH, Kim SR, Kwon YS. Depression and appetite: predictors of malnutrition in gynecologic cancer. Support Care Cancer. 2014; 22:3081–8.
Article
26. Giannousi Z, Gioulbasanis I, Pallis AG, Xyrafas A, Dalliani D, Kalbakis K, et al. Nutritional status, acute phase response and depression in met-astatic lung cancer patients: correlations and association prognosis. Support Care Cancer. 2012; 20:1823–9.
Article
27. Daudt HM, Cosby C, Dennis DL, Payeur N, Nurullah R. Nutritional and psychosocial status of colorectal cancer patients referred to an outpatient oncology clinic. Support Care Cancer. 2012; 20:1417–23.
Article
28. Langius JA, Zandbergen MC, Eerenstein SE, van Tulder MW, Leemans CR, Kramer MH, et al. Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review. Clin Nutr. 2013; 32:671–8.
Article
29. Hopkinson JB. Nutritional support of the elderly cancer patient: the role of the nurse. Nutrition. 2015; 31:598–602.
Article
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