Korean J Dermatol.  1997 Dec;35(6):1258-1262.

A Case of Cutaneous Pleomorphic T-cell Lymphoma

Affiliations
  • 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Pathology Seoul National University College of Medicine, Seoul, Korea.

Abstract

Cutaneous T-cell lymphomas other than mycosis fungoides and Sezary syndrome are heterogeneous; they deseve further scientific attention about their natural history and effective therapy. Pleomorphic T-cell lymphoma is a recently defined lymphoma type that can occur in the skin. We report the case of a man in whom such a tumor manifested itself with multiple subcutaneous lesions. The skin biopsy specimen showed diffuse dermal infiltration of atypical lymphocytes with highly pleomorphic nuclei. Testing for the antibody against HTLV-1 was negative and immunohistochemical staiiiing was compatible with pleomorphic T-cell lymphoma.

Keyword

HTLV-1; Pleotnorphic T-cell lymphoma

MeSH Terms

Biopsy
Human T-lymphotropic virus 1
Lymphocytes
Lymphoma
Lymphoma, T-Cell*
Lymphoma, T-Cell, Cutaneous
Mycosis Fungoides
Natural History
Sezary Syndrome
Skin
T-Lymphocytes*
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