J Korean Soc Radiol.  2012 Jul;67(1):53-56.

Single Metastatic Renal Cell Carcinoma in Gallbladder: A Case Report

• Kim EY
• Cho BS
• Kang MH
• Lee SY
• Yi KS
• Park KS
• Sung RH

Abstract

Renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancy. 25% to 57% of RCC patients exhibit overt evidence of metastatic disease at initial presentation. Metastases to the gallbladder is uncommon and usually detected in only 0.4-0.6% of autopsies. We report the case of a 58-year-old man who presented with a metastasis in the gallbladder from RCC. He had undergone went a right nephrectomy four years ago. There was no evidence of metastasis. A follow-up abdomen CT scan taken three years after operation showed a polypoid lesion within the gallbladder. The size of the polypoid lesion had increased at the follow-up CT and the enhancement pattern of lesion became similar to that of RCC. A Cholecystectomy was performed. Histopathological examination revealed the polyp was clear cell carcinoma of metastatic origin from kidney.

MeSH Terms

Abdomen
Adult
Autopsy
Carcinoma, Renal Cell
Cholecystectomy
Follow-Up Studies
Gallbladder
Humans
Kidney
Middle Aged
Neoplasm Metastasis
Nephrectomy
Polyps

Reference

1. Park JS, Chae YS, Hong SJ, Shin DH, Choi JS, Kim BR. Metastatic renal cell carcinoma of the gallbladder. Yonsei Med J. 2003. 44:355–358.

2. Chung PH, Srinivasan R, Linehan WM, Pinto PA, Bratslavsky G. Renal cell carcinoma with metastases to the gallbladder: four cases from the National Cancer Institute (NCI) and review of the literature. Urol Oncol. 2011. [Epub ahead of print].

3. Limani K, Matos C, Hut F, Gelin M, Closset J. Metastatic carcinoma of the gallbladder after a renal cell carcinoma. Acta Chir Belg. 2003. 103:233–234.

4. Saitoh H. Distant metastasis of renal adenocarcinoma. Cancer. 1981. 48:1487–1491.

5. Bennington JL, Kradjian RM. Bennington JL, Kradjian RM, editors. Distribution of metastases from renal carcinoma. Renal carcinoma. 1967. Philadelphia: Saunders;156–166.

6. Garant M, Bonaldi VM, Taourel P, Pinsky MF, Bret PM. Enhancement patterns of renal masses during multiphase helical CT acquisitions. Abdom Imaging. 1998. 23:431–436.

7. Kim JK, Park SY, Shon JH, Cho KS. Angiomyolipoma with minimal fat: differentiation from renal cell carcinoma at biphasic helical CT. Radiology. 2004. 230:677–684.

8. Mechó S, Quiroga S, Cuéllar H, Sebastià C. Pancreatic metastasis of renal cell carcinoma: multidetector CT findings. Abdom Imaging. 2009. 34:385–389.

9. Griffin N, Gore ME, Sohaib SA. Imaging in metastatic renal cell carcinoma. AJR Am J Roentgenol. 2007. 189:360–370.