Allergy Asthma Respir Dis.  2018 Jul;6(4):229-233. 10.4168/aard.2018.6.4.229.

Ecthyma gangrenosum and agranulocytosis in a previously healthy 12-month-old girl: Report of 1 case with a literature review

Affiliations
  • 1Department of Pediatrics, Soonchunhyang Unversity College of Medicine, Cheonan, Korea. pjstable@schmc.ac.kr
  • 2Department of Dermatology, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 3Department of Orthopedic Surgery, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 4Department of Clinical Laboratory Medicine, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 5Department of Emergency Medicine, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.

Abstract

Ecthyma gangrenosum (EG) is a rare skin manifestation which starts with a maculopapular eruption and followed by a necrotic ulcer covered with black eschar. EG usually occurs in immunosuppressed patients with Pseudomonas aeruginosa sepsis. We present a previously healthy 12-month-old girl with EG by P. aeruginosa and agranulocytosis due to influenza A and then rhinovirus infection, without bacteremia. It is important for allergists to culture wound and differentiate EG from other skin disorders including Tsutsugamushi disease and initiate appropriate empiric antipseudomonal antibiotic treatment, and to evaluate for possible immunodeficiency, even in a healthy child.

Keyword

Ecthyma gangrenosum; Agranulocytosis; Pseudomonas aeruginosa
Full Text Links
  • AARD
Share
  • Twitter
  • Facebook
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr