J Korean Soc Echocardiogr.  1996 Jul;4(1):66-71. 10.4250/jkse.1996.4.1.66.

Assessment of Left Ventricular Diastolic Dysfunction by Intraventricular Dispersion of Early Diastolic Filling

• Kim BS
• Jang YW
• Lee JI
• Chung WT
• Kim MH
• Kim JS

• KMID: 2410407
• DOI: http://doi.org/10.4250/jkse.1996.4.1.66

Abstract

BACKGROUND
Analysis of mitral flow velocity pattern provides useful variables in the assessment of left ventricular diastolic dysfuntion, but are affected by loading conditions or presence of atrial fibrillation. Thus we assessed intraventricular diastolic flow velocity profile in order to assessment of left ventricular diastolic dysfuntion.
METHODS
The study population consisted of 20 subjects with normal left ventricular function(including 7 patients with atrial fibrillation only), 15 patients with hypertensive heart disease, and 14 patients with dilated cardiomyopathy. The flow velocity pattern at the mitral tip was recorded simultaneously with regional pulsed Doppler diastolic velocity patterns at 1, 2, or 3 cm from the mitral tip toward the apex.
RESULTS
Inteh normal subjects, early diastolic flow velocity at the mitral tip was maintained at the positions 1 to 3cm away from the tip into the left ventricular carvity. In patients with dilated cardiomyopathy or hypertensive heart disease, peak early diastolic flow velocity decreased form the mitral tip toward the apex more progressively than in the subjects with normal left ventricular function. The same findings were obtained in selected patients group with atrial fibrillation or a normalized mitral flow velocity pattern.
CONCLUSION
The assessments of the intraventricular dispersion in peak early diastolic flow velocity may be useful in detecting left ventricular diastolic dysfuntion, particularly in patients with atrial fibrillation or a normalized mitral flow velocity pattern.

Keyword

Diastilic dysfuction; Interaventricular dispersion

MeSH Terms

Atrial Fibrillation
Cardiomyopathy, Dilated
Heart Diseases
Humans
Ventricular Function, Left

Figure

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  Fig. 1. Comparison of ratio of regional peak early diastolic flow velocity to E among subjects with normal LV function, patients with hypertensive heart disease (HHD), and Patients with dilated cardiomyopathy (DCMP). Values are mean.

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  Fig. 2. Comparison of ratio of regional peak early diastolic flow velocity to E among subjects with normal LV function, patients with dilated cardiomyopathy (DCMP) with E/A ratio of > 1, and with E/A ratio of <1. Values are mean.

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  Fig. 3. Comparison of ratio of regional peak early diastolic flow velocity to E among patients with Af only, patients with hypertensive heart disease(HHD), and Af, and patients with dilated cardiomyopathy (DCMP) and with Af. Values are mean.

Reference

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