Korean J Ophthalmol.  2018 Apr;32(2):140-146. 10.3341/kjo.2017.0085.

Visual Recovery after Macular Hole Surgery and Related Prognostic Factors

Affiliations
  • 1Department of Ophthalmology, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 2Department of Ophthalmology, Institute of Vision Research, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. SEMEKIM@yuhs.ac
  • 3Siloam Eye Hospital, Seoul, Korea.

Abstract

PURPOSE
To describe the visual recovery and prognostic factors after macular hole surgery.
METHODS
A retrospective chart review was conducted. Charts of patients with idiopathic macular holes who underwent surgery by a single surgeon at Severance Hospital between January 1, 2013 and July 31, 2015 were reviewed. The best-corrected visual acuity (BCVA) score was recorded preoperatively and at 1 day and 1, 3, 6, 9, and 12 months after surgery. The variables of age, sex, macular hole size, basal hole diameter, choroidal thickness, and axial length were also noted.
RESULTS
Twenty-six eyes of 26 patients were evaluated. Twenty-five patients (96.2%) showed successful macular hole closure after the primary operation. The BCVA stabilized 6 months postoperatively. A large basal hole diameter (p = 0.006) and thin choroid (p = 0.005) were related to poor visual outcomes. Poor preoperative BCVA (p < 0.001) and a thick choroid (p = 0.020) were associated with greater improvement in BCVA after surgery.
CONCLUSIONS
Visual acuity stabilized by 6 months after macular hole surgery. Choroidal thickness was a protective factor for final BCVA and visual improvement after the operation.

Keyword

Choroid; Retinal perforations; Visual acuity; Vitrectomy

MeSH Terms

Choroid
Humans
Protective Factors
Retinal Perforations*
Retrospective Studies
Visual Acuity
Vitrectomy

Figure

  • Fig. 1 Macular hole parameters measured in optical coherence tomography scans. a = hole size; b = basal hole size; c = choroidal thickness.

  • Fig. 2 Changes in best-corrected visual acuity (BCVA) after macular hole repair. logMAR = logarithm of the minimum angle of resolution. *p < 0.05, **p < 0.001.

  • Fig. 3 Analysis of correlation of choroidal thickness with (A) final best-corrected visual acuity (BCVA) and (B) changes in BCVA. logMAR = logarithm of the minimum angle of resolution.


Reference

1. Gaudric A, Haouchine B, Massin P, et al. Macular hole formation: new data provided by optical coherence tomography. Arch Ophthalmol. 1999; 117:744–751.
2. Haritoglou C, Gandorfer A, Gass CA, et al. Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophthalmol. 2002; 134:836–841.
Article
3. Brooks HL Jr. Macular hole surgery with and without internal limiting membrane peeling. Ophthalmology. 2000; 107:1939–1948.
Article
4. Vaziri K, Schwartz SG, Kishor KS, et al. Rates of reoperation and retinal detachment after macular hole surgery. Ophthalmology. 2016; 123:26–31.
Article
5. Ullrich S, Haritoglou C, Gass C, et al. Macular hole size as a prognostic factor in macular hole surgery. Br J Ophthalmol. 2002; 86:390–393.
Article
6. Sano M, Shimoda Y, Hashimoto H, Kishi S. Restored photoreceptor outer segment and visual recovery after macular hole closure. Am J Ophthalmol. 2009; 147:313–318.
Article
7. Itoh Y, Inoue M, Rii T, et al. Correlation between length of foveal cone outer segment tips line defect and visual acuity after macular hole closure. Ophthalmology. 2012; 119:1438–1446.
Article
8. Reibaldi M, Boscia F, Avitabile T, et al. Enhanced depth imaging optical coherence tomography of the choroid in idiopathic macular hole: a cross-sectional prospective study. Am J Ophthalmol. 2011; 151:112–117.
Article
9. Zeng J, Li J, Liu R, et al. Choroidal thickness in both eyes of patients with unilateral idiopathic macular hole. Ophthalmology. 2012; 119:2328–2333.
Article
10. Boonarpha N, Zheng Y, Stangos AN, et al. Standardization of choroidal thickness measurements using enhanced depth imaging optical coherence tomography. Int J Ophthalmol. 2015; 8:484–491.
11. Kelly NE, Wendel RT. Vitreous surgery for idiopathic macular holes: results of a pilot study. Arch Ophthalmol. 1991; 109:654–659.
12. Briand S, Chalifoux E, Tourville E, et al. Prospective randomized trial: outcomes of SF6 versus C3F8 in macular hole surgery. Can J Ophthalmol. 2015; 50:95–100.
Article
13. Shinoda H, Shinoda K, Satofuka S, et al. Visual recovery after vitrectomy for macular hole using 25-gauge instruments. Acta Ophthalmol. 2008; 86:151–155.
Article
14. Leonard RE 2nd, Smiddy WE, Flynn HW Jr, Feuer W. Long-term visual outcomes in patients with successful macular hole surgery. Ophthalmology. 1997; 104:1648–1652.
Article
15. Purtskhvanidze K, Treumer F, Junge O, et al. The long-term course of functional and anatomical recovery after macular hole surgery. Invest Ophthalmol Vis Sci. 2013; 54:4882–4891.
Article
16. Morgan CM, Schatz H. Involutional macular thinning: a pre-macular hole condition. Ophthalmology. 1986; 93:153–161.
17. Allen RD, Brown J Jr, Zwick H, et al. Laser-induced macular holes demonstrate impaired choroidal perfusion. Retina. 2004; 24:92–97.
Article
18. Aras C, Ocakoglu O, Akova N. Foveolar choroidal blood flow in idiopathic macular hole. Int Ophthalmol. 2004; 25:225–231.
Article
19. Wei WB, Xu L, Jonas JB, et al. Subfoveal choroidal thickness: the Beijing Eye Study. Ophthalmology. 2013; 120:175–180.
Article
20. Tan CS, Ouyang Y, Ruiz H, Sadda SR. Diurnal variation of choroidal thickness in normal, healthy subjects measured by spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2012; 53:261–266.
Article
21. Chakraborty R, Read SA, Collins MJ. Diurnal variations in axial length, choroidal thickness, intraocular pressure, and ocular biometrics. Invest Ophthalmol Vis Sci. 2011; 52:5121–5129.
Article
22. Sonoda S, Sakamoto T, Yamashita T, et al. Effect of intravitreal triamcinolone acetonide or bevacizumab on choroidal thickness in eyes with diabetic macular edema. Invest Ophthalmol Vis Sci. 2014; 55:3979–3985.
Article
23. Vance SK, Imamura Y, Freund KB. The effects of sildenafil citrate on choroidal thickness as determined by enhanced depth imaging optical coherence tomography. Retina. 2011; 31:332–335.
Article
24. Sogawa K, Nagaoka T, Takahashi A, et al. Relationship between choroidal thickness and choroidal circulation in healthy young subjects. Am J Ophthalmol. 2012; 153:1129–1132.
Article
25. Landa G, Gentile RC, Garcia PM, et al. External limiting membrane and visual outcome in macular hole repair: spectral domain OCT analysis. Eye (Lond). 2012; 26:61–69.
Article
Full Text Links
  • KJO
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr