Nucl Med Mol Imaging.  2017 Dec;51(4):364-367. 10.1007/s13139-016-0429-6.

Microcalcified Hepatic Metastases Incidentally Detected on F-18 NaF PET/CT in a Patient with Prostate Cancer

• Aktas GE
• Sarıkaya
• Can N
• Demir SS

• KMID: 2403514
• DOI: http://doi.org/10.1007/s13139-016-0429-6

Abstract

F-18 NaF PET/CT evaluation has gained importance in recent years. Achievements from F-18 NaF PET/CT are: higher sensitivity of positron imaging, higher target background ratio with higher tracer accumulation in bone hydroxyapatite and higher specificity through CT correlation. These properties have also given directions to new research fields based on imaging microcalcifications, very recently. A limited number of cases have reported the F-18 NaF uptake in macrocalcified soft tissue metastases. Although the presence of microcalcification was not proved; accumulation of F-18 NaF in the metastatic brain lesion with no visible calcification on the CT, in a patient with ductal breast carcinoma has also been reported. Herein we present a patient with microcalcified hepatic metastasis of prostate cancer incidentally detected on F-18 NaF PET/CT which was confirmed with histochemical staining.

Keyword

Calcification; Imaging; Metastasis; Positron-emission tomography; Prostate; Sodiumfluoride

MeSH Terms

Brain
Breast Neoplasms
Durapatite
Electrons
Humans
Neoplasm Metastasis*
Positron-Emission Tomography
Positron-Emission Tomography and Computed Tomography*
Prostate*
Prostatic Neoplasms*
Sensitivity and Specificity
Durapatite