Ultrasonography.  2018 Jan;37(1):25-35. 10.14366/usg.17037.

Contrast-enhanced ultrasonography of the liver using SonoVue

Affiliations
  • 1Ultrasound Unit, Infectious Diseases Department, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. giovanna.ferraioli@unipv.it
  • 2Interventional Ultrasound, Casa di Cura Igea, Milano, Italy.

Abstract

This review focuses on the use of contrast-enhanced ultrasonography (CEUS) with SonoVue (Bracco Imaging) for the diagnosis of focal liver lesions (FLLs), guidance during ablative treatment, and follow-up of liver tumors. Multicenter trials have shown that the performance of CEUS for the characterization of FLLs is similar to that of contrast-enhanced computed tomography or contrast-enhanced magnetic resonance imaging. CEUS with SonoVue has been effectively used for guiding the percutaneous treatment of malignant liver tumors that are invisible or poorly visualized in traditional gray-scale ultrasonography. Postprocedural CEUS may be used to detect and retreat residual viable tissue in the same ablative session. The use of CEUS for the assessment of diffuse liver disease is also discussed.

Keyword

Liver; Contrast-enhanced ultrasound; Liver tumors; Carcinoma, hepatocellular; Liver metastasis

MeSH Terms

Carcinoma, Hepatocellular
Diagnosis
Follow-Up Studies
Liver Diseases
Liver*
Magnetic Resonance Imaging
Multicenter Studies as Topic
Ultrasonography*
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