Clin Psychopharmacol Neurosci.  2017 Nov;15(4):313-319. 10.9758/cpn.2017.15.4.313.

Peripheral Signatures of Psychiatric Disorders: MicroRNAs

Affiliations
  • 1Department of Psychiatry, AfÅŸin State Hospital, AfÅŸin, KahramanmaraÅŸ, Turkey. dr.akif@gmail.com
  • 2Department of Child and Adolescent Pscyhiatry, Faculty of Medicine, Mersin University, Mersin, Turkey.
  • 3Department of Medical Genetics, Faculty of Medicine, Dicle Univesity, Diyarbakır, Turkey.
  • 4Department of Psychiatry, Faculty of Medicine, KahramanmaraÅŸ Sütçüİmam University, KahramanmaraÅŸ, Turkey.

Abstract

MicroRNAs (miRNAs) are 22 nucleotide long RNA transcripts, their synthesis starts in nucleus and continues in cytoplasm. As being critical for post-transcriptional regulators of gene expression they have been investigated in psychiatric disorders. There are numerous studies performed in peripheral tissues for psychiatric disorders. Here in this article, we aimed to review some common miRNAs denoted significant in at least two studies and their relevance to psychiatric research. We focused on miR-320, miR-106, miR-34, miR-223, miR-107, and miR-134.

Keyword

MicroRNA; Psychiatry; Blood; Plasma; Serum; Biomarker
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